期刊
NATURE STRUCTURAL & MOLECULAR BIOLOGY
卷 20, 期 12, 页码 1348-1350出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/nsmb.2727
关键词
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Faithful bypass of replication forks encountering obstructive DNA lesions is essential to prevent fork collapse and cell death. PrimPol is a new human primase and translesion polymerase that is able to bypass fork-blocking UV-induced lesions and to restart replication by origin-independent repriming.
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