期刊
NATURE STRUCTURAL & MOLECULAR BIOLOGY
卷 19, 期 6, 页码 594-601出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/nsmb.2301
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资金
- Howard Hughes Medical Institute Funding Source: Medline
- NIGMS NIH HHS [R01 GM059425] Funding Source: Medline
There are three predominant forms of co-translational mRNA surveillance: nonsense-mediated decay (NMD), no-go decay (NGD) and nonstop decay (NSD). Although discussion of these pathways often focuses on mRNA fate, there is growing consensus that there are other important outcomes of these processes that must be simultaneously considered. Here, we seek to highlight similarities between NMD, NGD and NSD and their probable origins on the ribosome during translation.
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