期刊
NATURE STRUCTURAL & MOLECULAR BIOLOGY
卷 19, 期 1, 页码 5-7出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/nsmb.2220
关键词
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Oncogene-induced replication stress and DNA damage are among the hallmarks of cancer. A recent study explores how different levels of replication stress affect animal development and tumorigenesis, and how targeting of the replication stress-signaling pathway of ATR and Chk1 kinases can be exploited for selective killing of cancer cells.
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