相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。A phase I study of sorafenib and vorinostat in patients with advanced solid tumors with expanded cohorts in renal cell carcinoma and non-small cell lung cancer
A. Dasari et al.
INVESTIGATIONAL NEW DRUGS (2013)
Nuclear export of proteins and drug resistance in cancer
Joel G. Turner et al.
BIOCHEMICAL PHARMACOLOGY (2012)
Annual Report to the Nation on the status of cancer, 1975-2008, featuring cancers associated with excess weight and lack of sufficient physical activity
Christie Eheman et al.
CANCER (2012)
Genome-wide microRNA profiles identify miR-378 as a serum biomarker for early detection of gastric cancer
Hanshao Liu et al.
CANCER LETTERS (2012)
Kidney Tumor Biomarkers Revealed by Simultaneous Multiple Matrix Metabolomics Analysis
Sheila Ganti et al.
CANCER RESEARCH (2012)
Identification of Suitable Reference Genes for qPCR Analysis of Serum microRNA in Gastric Cancer Patients
Jianning Song et al.
DIGESTIVE DISEASES AND SCIENCES (2012)
Cardiac Insulin Resistance and MicroRNA Modulators
Lakshmi Pulakat et al.
EXPERIMENTAL DIABETES RESEARCH (2012)
Phase I Study of RO4929097, a Gamma Secretase Inhibitor of Notch Signaling, in Patients With Refractory Metastatic or Locally Advanced Solid Tumors
Anthony W. Tolcher et al.
JOURNAL OF CLINICAL ONCOLOGY (2012)
Circulating miR-378 and miR-451 in serum are potential biomarkers for renal cell carcinoma
Martina Redova et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2012)
Novel Therapies for Metastatic Renal Cell Carcinoma: Efforts to Expand beyond the VEGF/mTOR Signaling Paradigm
Sumanta Kumar Pal et al.
MOLECULAR CANCER THERAPEUTICS (2012)
Tumor Immunotherapy Directed at PD-1
Antoni Ribas
NEW ENGLAND JOURNAL OF MEDICINE (2012)
Safety and Activity of Anti-PD-L1 Antibody in Patients with Advanced Cancer
Julie R. Brahmer et al.
NEW ENGLAND JOURNAL OF MEDICINE (2012)
Safety, Activity, and Immune Correlates of Anti-PD-1 Antibody in Cancer
Suzanne L. Topalian et al.
NEW ENGLAND JOURNAL OF MEDICINE (2012)
Class I Histone Deacetylase Inhibitor Entinostat Suppresses Regulatory T Cells and Enhances Immunotherapies in Renal and Prostate Cancer Models
Li Shen et al.
PLOS ONE (2012)
ELR510444 Inhibits Tumor Growth and Angiogenesis by Abrogating HIF Activity and Disrupting Microtubules in Renal Cell Carcinoma
Jennifer S. Carew et al.
PLOS ONE (2012)
14-3-3 Protein beta/alpha as a urinary biomarker for renal cell carcinoma: proteomic analysis of cyst fluid
Satoru Minamida et al.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2011)
CBS9106 is a novel reversible oral CRM1 inhibitor with CRM1 degrading activity
Keiichi Sakakibara et al.
BLOOD (2011)
Phase 1 Dose-Escalation Trial of Tremelimumab Plus Sunitinib in Patients With Metastatic Renal Cell Carcinoma
Brian I. Rini et al.
CANCER (2011)
Sorafenib attenuates p21 in kidney cancer cells and augments cell death in combination with DNA-damaging chemotherapy
Hiromi Inoue et al.
CANCER BIOLOGY & THERAPY (2011)
p53-dependent anticancer effects of leptomycin B on lung adenocarcinoma
Changxia Shao et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2011)
The Epidemiology of Renal Cell Carcinoma
Borje Ljungberg et al.
EUROPEAN UROLOGY (2011)
First-in-Man Clinical Trial of the Oral Pan-AKT Inhibitor MK-2206 in Patients With Advanced Solid Tumors
Timothy A. Yap et al.
JOURNAL OF CLINICAL ONCOLOGY (2011)
Comparative effectiveness of axitinib versus sorafenib in advanced renal cell carcinoma (AXIS): a randomised phase 3 trial
Brian I. Rini et al.
LANCET (2011)
The B-Raf Status of Tumor Cells May Be a Significant Determinant of Both Antitumor and Anti-Angiogenic Effects of Pazopanib in Xenograft Tumor Models
Brunilde Gril et al.
PLOS ONE (2011)
Urine metabolomics for kidney cancer detection and biomarker discovery
Sheila Ganti et al.
UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS (2011)
Discovery of Small Molecule c-Met Inhibitors: Evolution and Profiles of Clinical Candidates
Ted L. Underiner et al.
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY (2010)
Sunitinib Acts Primarily on Tumor Endothelium rather than Tumor Cells to Inhibit the Growth of Renal Cell Carcinoma
Dan Huang et al.
CANCER RESEARCH (2010)
Examination of the expanding pathways for the regulation of p21 expression and activity
Yong-Sam Jung et al.
CELLULAR SIGNALLING (2010)
Vorinostat Enhances the Activity of Temsirolimus in Renal Cell Carcinoma Through Suppression of Survivin Levels
Devalingam Mahalingam et al.
CLINICAL CANCER RESEARCH (2010)
A Phase II Clinical Trial of Ixabepilone (Ixempra; BMS-247550; NSC 710428), an Epothilone B Analog, in Patients with Metastatic Renal Cell Carcinoma
Hui Huang et al.
CLINICAL CANCER RESEARCH (2010)
An allosteric mechanism to displace nuclear export cargo from CRM1 and RanGTP by RanBP1
Masako Koyama et al.
EMBO JOURNAL (2010)
Peroxisome Proliferator-Activated Receptor-alpha Control of Lipid and Glucose Metabolism in Human White Adipocytes
Carole Ribet et al.
ENDOCRINOLOGY (2010)
Phase I Study of Single-Agent Anti-Programmed Death-1 (MDX-1106) in Refractory Solid Tumors: Safety, Clinical Activity, Pharmacodynamics, and Immunologic Correlates
Julie R. Brahmer et al.
JOURNAL OF CLINICAL ONCOLOGY (2010)
Novel histone deacetylase inhibitors in clinical trials as anti-cancer agents
Jiahuai Tan et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2010)
VHL and HIF signalling in renal cell carcinogenesis
Marcella M. Baldewijns et al.
JOURNAL OF PATHOLOGY (2010)
MicroRNA-451 Regulates LKB1/AMPK Signaling and Allows Adaptation to Metabolic Stress in Glioma Cells
Jakub Godlewski et al.
MOLECULAR CELL (2010)
Epidemiology and risk factors for kidney cancer
Wong-Ho Chow et al.
NATURE REVIEWS UROLOGY (2010)
Urinary Biomarkers for the Early Diagnosis of Kidney Cancer
Jeremiah J. Morrissey et al.
MAYO CLINIC PROCEEDINGS (2010)
Pathway Signature and Cellular Differentiation in Clear Cell Renal Cell Carcinoma
Han W. Tun et al.
PLOS ONE (2010)
Characterizing the Effects of the Juxtamembrane Domain on Vascular Endothelial Growth Factor Receptor-2 Enzymatic Activity, Autophosphorylation, and Inhibition by Axitinib
James Solowiej et al.
BIOCHEMISTRY (2009)
Quantitative protein expression profiling of 14-3-3 isoforms in human renal carcinoma shows 14-3-3 epsilon is involved in limitedly increasing renal cell proliferation
Shufang Liang et al.
ELECTROPHORESIS (2009)
Expression of Aquaporin 1 in Primary Renal Tumors: A Prognostic Indicator for Clear-Cell Renal Cell Carcinoma
Ying Huang et al.
EUROPEAN UROLOGY (2009)
The detection of differentially expressed microRNAs from the serum of ovarian cancer patients using a novel real-time PCR platform
Kimberly E. Resnick et al.
GYNECOLOGIC ONCOLOGY (2009)
The Karyopherin proteins, Crm1 and Karyopherin β1, are overexpressed in cervical cancer and are critical for cancer cell survival and proliferation
Pauline J. Van der Watt et al.
INTERNATIONAL JOURNAL OF CANCER (2009)
The histone deacetylase inhibitor valproic acid alters growth properties of renal cell carcinoma in vitro and in vivo
Jon Jones et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2009)
Human Activated T Lymphocytes Modulate IDO Expression in Tumors through Th1/Th2 Balance
Jessica Godin-Ethier et al.
JOURNAL OF IMMUNOLOGY (2009)
Grade-dependent Proteomics Characterization of Kidney Cancer
Bertrand Perroud et al.
MOLECULAR & CELLULAR PROTEOMICS (2009)
The pattern of excess cancer in dialysis and transplantation
John H. Stewart et al.
NEPHROLOGY DIALYSIS TRANSPLANTATION (2009)
Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions
Chunaram Choudhary et al.
SCIENCE (2009)
The LKB1-AMPK pathway: metabolism and growth control in tumour suppression
David B. Shackelford et al.
NATURE REVIEWS CANCER (2009)
Class I histone deacetylases 1, 2 and 3 are highly expressed in renal cell cancer
Florian R. Fritzsche et al.
BMC CANCER (2008)
Cancer-specific Survival Outcomes Among Patients Treated During the Cytokine Era of Kidney Cancer (1989-2005) A Benchmark for Emerging Targeted Cancer Therapies
Arie S. Belldegrun et al.
CANCER (2008)
Expression of the nuclear export protein chromosomal region maintenance/exportin 1/Xpo1 is a prognostic factor in human ovarian cancer
Aurelia Noske et al.
CANCER (2008)
Histone deacetylase inhibitors: Mechanisms of cell death and promise in combination cancer therapy
Jennifer S. Carew et al.
CANCER LETTERS (2008)
Temsirolimus, an inhibitor of mammalian target of rapamycin
Brian I. Rini
CLINICAL CANCER RESEARCH (2008)
Regulation of hematopoietic stem cells by the steel factor/KIT signaling pathway
David Kent et al.
CLINICAL CANCER RESEARCH (2008)
Improved identification of von Hippel-Lindau gene alterations in clear cell renal tumors
Michael L. Nickerson et al.
CLINICAL CANCER RESEARCH (2008)
Phase I safety and pharmacokinetic study of CT-011, a humanized antibody interacting with PD-1, in patients with advanced hematologic malignancies
Raanan Berger et al.
CLINICAL CANCER RESEARCH (2008)
CRM1-Mediated Nuclear Export of Proteins and Drug Resistance in Cancer
Joel G. Turner et al.
CURRENT MEDICINAL CHEMISTRY (2008)
Antisense attenuation of p21 sensitizes kidney cancer to apoptosis in response to conventional DNA damaging chemotherapy associated with enhancement of phospho-p53
See-Hyoung Park et al.
JOURNAL OF UROLOGY (2008)
Efficacy of everolimus in advanced renal cell carcinoma:: a double-blind, randomised, placebo-controlled phase III trial
Robert J. Motzer et al.
LANCET (2008)
Circulating microRNAs as stable blood-based markers for cancer detection
Patrick S. Mitchell et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
IDO-expressing regulatory dendritic cells in cancer and chronic infection
Alexey Popov et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2008)
MicroRNA-378 promotes cell survival, tumor growth, and angiogenesis by targeting SuFu and Fus-1 expression
Daniel Y. Lee et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Hypoxia-inducible factor 1α in clear cell renal cell carcinoma
Tobias Klatte et al.
CLINICAL CANCER RESEARCH (2007)
Shedding of the urinary biomarker kidney injury molecule-1 (KIM-1) is regulated by MAP kinases and juxtamembrane region
Zhiwei Zhang et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2007)
Evaluation of HIF-1 inhibitors as anticancer agents
Gregg L. Semenza
DRUG DISCOVERY TODAY (2007)
Vorinostat: a new oral histone deacetylase inhibitor approved for cutaneous T-cell lymphoma
Madeleine Duvic et al.
EXPERT OPINION ON INVESTIGATIONAL DRUGS (2007)
Histone deacetylase 2 modulates p53 transcriptional activities through regulation of p53-DNA binding activity
Kelly Lynn Harms et al.
CANCER RESEARCH (2007)
PD-1 is expressed by tumor-infiltrating immune cells and is associated with poor outcome for patients with renal cell carcinoma
R. Houston Thompson et al.
CLINICAL CANCER RESEARCH (2007)
Expression of adipose differentiation-related protein: A predictor of cancer-specific survival in clear cell renal carcinoma
Masahiro Yao et al.
CLINICAL CANCER RESEARCH (2007)
p21 is a prognostic marker for renal cell carcinoma: Implications for novel therapeutic approaches
Robert H. Weiss et al.
JOURNAL OF UROLOGY (2007)
Activation of the mTOR signaling pathway in renal clear cell carcinoma
Victoria A. Robb et al.
JOURNAL OF UROLOGY (2007)
Cancer incidence before and after kidney transplantation
Claire M. Vajdic et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2006)
Peroxisome proliferator-activated receptor α activation decreases metastatic potential of melanoma cells in vitro via down-regulation of Akt
Maja Grabacka et al.
CLINICAL CANCER RESEARCH (2006)
Tumor B7-H1 is associated with poor prognosis in renal cell carcinoma patients with long-term follow-up
RH Thompson et al.
CANCER RESEARCH (2006)
Immune suppression in cancer: Effects on immune cells, mechanisms and future therapeutic intervention
TL Whiteside
SEMINARS IN CANCER BIOLOGY (2006)
Kidney cancer: Identification of novel targets for therapy
RH Weiss et al.
KIDNEY INTERNATIONAL (2006)
Peroxisome proliferator-activated receptor-α and liver cancer:: where do we stand?
JM Peters et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2005)
Human kidney injury molecule-1 is a tissue and urinary tumor marker of renal cell carcinoma
WK Han et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2005)
Renal cell carcinoma in relation to cigarette smoking: Meta-analysis of 24 studies
JD Hunt et al.
INTERNATIONAL JOURNAL OF CANCER (2005)
Gene expression analysis of renal carcinoma: adipose differentiation-related protein as a potential diagnostic and prognostic biomarker for clear-cell renal carcinoma
M Yao et al.
JOURNAL OF PATHOLOGY (2005)
Phase II trial of bortezomib for patients with advanced renal cell carcinoma
GV Kondagunta et al.
JOURNAL OF CLINICAL ONCOLOGY (2004)
Opinion - Switching on kinases: oncogenic activation of BRAF and the PDGFR family
NJ Dibb et al.
NATURE REVIEWS CANCER (2004)
BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis
SM Wilhelm et al.
CANCER RESEARCH (2004)
VEGF-receptor signal transduction
MJ Cross et al.
TRENDS IN BIOCHEMICAL SCIENCES (2003)
Peroxisome proliferator-activated receptor β expression in human breast epithelial cell lines of tumorigenic and non-tumorigenic origin
KM Suchanek et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2002)
Peroxisome proliferator-activated receptor α in the human breast cancer cell lines MCF-7 and MDA-MB-231
KM Suchanek et al.
MOLECULAR CARCINOGENESIS (2002)
Endogenous kynurenines as targets for drug discovery and development
TW Stone et al.
NATURE REVIEWS DRUG DISCOVERY (2002)
Kidney Injury Molecule-1 (KIM-1): A novel biomarker for human renal proximal tubule injury
WK Han et al.
KIDNEY INTERNATIONAL (2002)
Design and discovery of small molecules targeting Raf-1 kinase
TB Lowinger et al.
CURRENT PHARMACEUTICAL DESIGN (2002)
Renal epithelial neoplasms: The diagnostic implications of electron microscopic study in 55 cases
B Krishnan et al.
HUMAN PATHOLOGY (2002)