4.5 Editorial Material

A Notch in the joint that exacerbates osteoarthritis

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NATURE REVIEWS RHEUMATOLOGY
卷 14, 期 10, 页码 563-564

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NATURE PUBLISHING GROUP
DOI: 10.1038/s41584-018-0076-7

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资金

  1. Excellence of Science Grant Join-t-against-OA
  2. Flanders Research Foundation (FWO Vlaanderen)
  3. KU Leuven [C1]
  4. Celgene

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Tight regulation of signalling cascades is vital for the correct development and function of bones and joints. A new study suggests that Notch signalling might join the likes of the transforming growth factor superfamily and Wnt signalling cascades as having an important function in joint homeostasis and disease.

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