期刊
NATURE REVIEWS NEUROSCIENCE
卷 14, 期 1, 页码 63-69出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/nrn3361
关键词
-
资金
- INSERM
- Aix-Marseille Universite
- Centre National de la Recherche Scientifique
- Agence Nationale de la Recherche [ANR 11 BSV4 016 01]
- Fondation pour le Recherche Medicale
- French Ministry of Research
Synaptic transmission in the brain generally depends on action potentials. However, recent studies indicate that subthreshold variation in the presynaptic membrane potential also determines spike-evoked transmission. The informational content of each presynaptic action potential is therefore greater than initially expected. The contribution of this synaptic property, which is a fast (from 0.01 to 10 s) and state-dependent modulation of functional coupling, has been largely underestimated and could have important consequences for our understanding of information processing in neural networks. We discuss here how the membrane voltage of the presynaptic terminal might modulate neurotransmitter release by mechanisms that do not involve a change in presynaptic Ca2+ influx.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据