期刊
NATURE REVIEWS NEUROSCIENCE
卷 12, 期 9, 页码 509-523出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/nrn3084
关键词
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资金
- US National Institutes of Health [MH073245, DC009947]
- US National Science Foundation [SBE-0542, 013]
- UK Engineering and Physical Sciences Research Council [EP/I005102]
- Royal Society
- UK Biotechnology and Biological Sciences Research Council [BBS/B/09, 325]
- Wellcome Trust [070, 380/Z/03/Z]
- EPSRC [EP/I005102/1] Funding Source: UKRI
- MRC [G0700976] Funding Source: UKRI
- Biotechnology and Biological Sciences Research Council [BBS/B/09325] Funding Source: researchfish
- Engineering and Physical Sciences Research Council [EP/I005102/1] Funding Source: researchfish
- Medical Research Council [G0700976] Funding Source: researchfish
The brain continuously adapts its processing machinery to behavioural demands. To achieve this, it rapidly modulates the operating mode of cortical circuits, controlling the way that information is transformed and routed. This article will focus on two experimental approaches by which the control of cortical information processing has been investigated: the study of state-dependent cortical processing in rodents and attention in the primate visual system. Both processes involve a modulation of low-frequency activity fluctuations and spiking correlation, and are mediated by common receptor systems. We suggest that selective attention involves processes that are similar to state change, and that operate at a local columnar level to enhance the representation of otherwise non-salient features while suppressing internally generated activity patterns.
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