相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Aggregation of αSynuclein promotes progressive in vivo neurotoxicity in adult rat dopaminergic neurons
Grit Taschenberger et al.
ACTA NEUROPATHOLOGICA (2012)
Parkinson's disease is not associated with gastrointestinal myenteric ganglion neuron loss
Dana M. Annerino et al.
ACTA NEUROPATHOLOGICA (2012)
Spinal cord lesions in sporadic Parkinson's disease
Kelly Del Tredici et al.
ACTA NEUROPATHOLOGICA (2012)
Pale Neurites, Premature a-Synuclein Aggregates with Centripetal Extension from Axon Collaterals
Toshiro Kanazawa et al.
BRAIN PATHOLOGY (2012)
Direct Observation of the Interconversion of Normal and Toxic Forms of α-Synuclein
Nunilo Cremades et al.
CELL (2012)
Evaluation of the Braak hypothesis: how far can it explain the pathogenesis of Parkinson's disease?
Glenda Halliday et al.
EXPERT REVIEW OF NEUROTHERAPEUTICS (2012)
Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in mice
Kelvin C. Luk et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2012)
Systematic Mutagenesis of α-Synuclein Reveals Distinct Sequence Requirements for Physiological and Pathological Activities
Jacqueline Burre et al.
JOURNAL OF NEUROSCIENCE (2012)
Lewy pathology and neurodegeneration in premotor Parkinson's disease
Kelly Del Tredici et al.
MOVEMENT DISORDERS (2012)
Is alpha-synuclein in the colon a biomarker for premotor Parkinson's Disease? Evidence from 3 cases
Kathleen M. Shannon et al.
MOVEMENT DISORDERS (2012)
The neuropathology of genetic Parkinson's disease
Markos Poulopoulos et al.
MOVEMENT DISORDERS (2012)
Prion-like acceleration of a synucleinopathy in a transgenic mouse model
Anne-Laure Mougenot et al.
NEUROBIOLOGY OF AGING (2012)
A comparison between rectal and colonic biopsies to detect Lewy pathology in Parkinson's disease
Helene Pouclet et al.
NEUROBIOLOGY OF DISEASE (2012)
A Unifying Role for Prions in Neurodegenerative Diseases
Stanley B. Prusiner
SCIENCE (2012)
PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65
Chandana Kondapalli et al.
OPEN BIOLOGY (2012)
The incidence of Parkinsonism in patients with type 1 Gaucher disease: Data from the ICGG Gaucher Registry
Barry Rosenbloom et al.
BLOOD CELLS MOLECULES AND DISEASES (2011)
Generation of Isogenic Pluripotent Stem Cells Differing Exclusively at Two Early Onset Parkinson Point Mutations
Frank Soldner et al.
CELL (2011)
E46K Human α-Synuclein Transgenic Mice Develop Lewy-like and Tau Pathology Associated with Age-dependent, Detrimental Motor Impairment
Kristel L. Emmer et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
α-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells
Christian Hansen et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
Dementia in Parkinson's disease: a 20-year neuropsychological study (Sydney Multicentre Study)
W. G. J. Reid et al.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2011)
α-Syn Suppression Reverses Synaptic and Memory Defects in a Mouse Model of Dementia with Lewy Bodies
Youngshin Lim et al.
JOURNAL OF NEUROSCIENCE (2011)
Enhanced Phosphatase Activity Attenuates α-Synucleinopathy in a Mouse Model
Kang-Woo Lee et al.
JOURNAL OF NEUROSCIENCE (2011)
Mechanisms of mitophagy
Richard J. Youle et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2011)
Transfer of host-derived alpha synuclein to grafted dopaminergic neurons in rat
Jeffrey H. Kordower et al.
NEUROBIOLOGY OF DISEASE (2011)
Exogenous α-Synuclein Fibrils Induce Lewy Body Pathology Leading to Synaptic Dysfunction and Neuron Death
Laura A. Volpicelli-Daley et al.
NEURON (2011)
Passive Immunization Reduces Behavioral and Neuropathological Deficits in an Alpha-Synuclein Transgenic Model of Lewy Body Disease
Eliezer Masliah et al.
PLOS ONE (2011)
Exploring the link between glucocerebrosidase mutations and parkinsonism
Wendy Westbroek et al.
TRENDS IN MOLECULAR MEDICINE (2011)
Parkinson's disease induced pluripotent stem cells with triplication of the α-synuclein locus
Michael J. Devine et al.
NATURE COMMUNICATIONS (2011)
Cell type specific sequestration of choline acetyltransferase and tyrosine hydroxylase within Lewy bodies
Brittany N. Dugger et al.
ACTA NEUROPATHOLOGICA (2010)
Lewy pathology in the submandibular gland of individuals with incidental Lewy body disease and sporadic Parkinson's disease
Kelly Del Tredici et al.
ACTA NEUROPATHOLOGICA (2010)
Glucocerebrosidase is present in α-synuclein inclusions in Lewy body disorders
Ozlem Goker-Alpan et al.
ACTA NEUROPATHOLOGICA (2010)
SNARE protein redistribution and synaptic failure in a transgenic mouse model of Parkinson's disease
Pablo Garcia-Reitboeck et al.
BRAIN (2010)
PINK1-linked parkinsonism is associated with Lewy body pathology
Lluis Samaranch et al.
BRAIN (2010)
Association of the human leucocyte antigen region with susceptibility to Parkinson's disease
Misuzu Saiki et al.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2010)
Neuropathological assessment of Parkinson's disease: refining the diagnostic criteria (vol 8, pg 1150, 2009)
D. W. Dickson et al.
LANCET NEUROLOGY (2010)
Who was the Man Who Discovered the Lewy Bodies''?
Antonio M. Rodrigues e Silva et al.
MOVEMENT DISORDERS (2010)
Characterization of Lewy Body Pathology in 12-and 16-Year-Old Intrastriatal Mesencephalic Grafts Surviving in a Patient With Parkinson's Disease
Jia-Yi Li et al.
MOVEMENT DISORDERS (2010)
Evidence in Favor of Braak Staging of Parkinson's Disease
Dennis W. Dickson et al.
MOVEMENT DISORDERS (2010)
Molecular and clinical prodrome of Parkinson disease: implications for treatment
Anthony H. V. Schapira et al.
NATURE REVIEWS NEUROLOGY (2010)
A stable proportion of Lewy body bearing neurons in the substantia nigra suggests a model in which the Lewy body causes neuronal death
Sandrine Greffard et al.
NEUROBIOLOGY OF AGING (2010)
Progression of Parkinson's Disease Pathology Is Reproduced by Intragastric Administration of Rotenone in Mice
Francisco Pan-Montojo et al.
PLOS ONE (2010)
α-Synuclein Suppression by Targeted Small Interfering RNA in the Primate Substantia Nigra
Alison L. McCormack et al.
PLOS ONE (2010)
A timeline for Parkinson's disease
Christopher H. Hawkes et al.
PARKINSONISM & RELATED DISORDERS (2010)
αβγ-Synuclein triple knockout mice reveal age-dependent neuronal dysfunction
Becket Greten-Harrison et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
The propagation of prion-like protein inclusions in neurodegenerative diseases
Michel Goedert et al.
TRENDS IN NEUROSCIENCES (2010)
Neuropothological assessment of Parkinson's disease: refining the diagnostic criteria. (vol 8, pg 1150, 2009)
D. W. Dickson et al.
LANCET NEUROLOGY (2010)
Diminished tyrosine hydroxylase immunoreactivity in the cardiac conduction system and myocardium in Parkinson's disease: an anatomical study
Estifanos Ghebremedhin et al.
ACTA NEUROPATHOLOGICA (2009)
Unified staging system for Lewy body disorders: correlation with nigrostriatal degeneration, cognitive impairment and motor dysfunction
Thomas G. Beach et al.
ACTA NEUROPATHOLOGICA (2009)
SNCA Variants Are Associated with Increased Risk for Multiple System Atrophy
Sonja W. Scholz et al.
ANNALS OF NEUROLOGY (2009)
Overview of the Extranigral Aspects of Parkinson Disease
Shen-Yang Lim et al.
ARCHIVES OF NEUROLOGY (2009)
Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease
Wataru Satake et al.
NATURE GENETICS (2009)
Genome-wide association study reveals genetic risk underlying Parkinson's disease
Javier Simon-Sanchez et al.
NATURE GENETICS (2009)
Multicenter Analysis of Glucocerebrosidase Mutations in Parkinson's Disease
E. Sidransky et al.
NEW ENGLAND JOURNAL OF MEDICINE (2009)
Genetic Variants of the α-Synuclein Gene SNCA Are Associated with Multiple System Atrophy
Ammar Al-Chalabi et al.
PLOS ONE (2009)
Neuropathology of non-motor features of Parkinson disease
Dennis W. Dickson et al.
PARKINSONISM & RELATED DISORDERS (2009)
Inclusion formation and neuronal cell death through neuron-to-neuron transmission of α-synuclein
Paula Desplats et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Neuropathological assessment of Parkinson's disease: refining the diagnostic criteria
Dennis W. Dickson et al.
LANCET NEUROLOGY (2009)
Evidence that incidental Lewy body disease is pre-symptomatic Parkinson's disease
Dennis W. Dickson et al.
ACTA NEUROPATHOLOGICA (2008)
A systematic RNAi screen reveals involvement of endocytic pathway in neuronal dysfunction in α-synuclein transgenic C.elegans
Tomoki Kuwahara et al.
HUMAN MOLECULAR GENETICS (2008)
Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation
Jia-Yi Li et al.
NATURE MEDICINE (2008)
Lewy body-like pathology in long-term embryonic nigral transplants in Parkinson's disease
Jeffrey H. Kordower et al.
NATURE MEDICINE (2008)
The fold of α-synuclein fibrils
Marcal Vilar et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Reduced striatal tyrosine hydroxylase in incidental Lewy body disease
Thomas Gerald Beach et al.
ACTA NEUROPATHOLOGICA (2008)
Analysis of the adrenal gland is useful for evaluating pathology of the peripheral autonomic nervous system in Lewy body disease
Yuichi Fumimura et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2007)
Aggregated α-synuclein mediates dopaminergic neurotoxicity in vivo
Magali Periquet et al.
JOURNAL OF NEUROSCIENCE (2007)
Parkinson's disease: lesions in dorsal horn layer I, involvement of parasympathetic and sympathetic pre- and postganglionic neurons
Heiko Braak et al.
ACTA NEUROPATHOLOGICA (2007)
Stanley Fahn Lecture 2005:: The staging procedure for the inclusion body pathology associated with sporadic Parkinson's disease reconsidered
Heiko Braak et al.
MOVEMENT DISORDERS (2006)
Phosphorylation of Ser-129 is the dominant pathological modification of α-synuclein in familial and sporadic Lewy body disease
John P. Anderson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Alzheimer disease with amygdala Lewy bodies:: A distinct form of α-synucleinopathy
Hirotake Uchikado et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2006)
Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin
Ira E. Clark et al.
NATURE (2006)
Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin
Jeehye Park et al.
NATURE (2006)
α-Synuclein pathology of the spinal and peripheral autonomic nervous system in neurologically unimpaired elderly subjects
A Bloch et al.
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2006)
Small molecule inhibitors of α-synuclein filament assembly
Masami Masuda et al.
BIOCHEMISTRY (2006)
Pathological changes in dopaminergic nerve cells of the substantia nigra and olfactory bulb in mice transgenic for truncated human α-synuclein (1-120):: Implications for Lewy body disorders
GK Tofaris et al.
JOURNAL OF NEUROSCIENCE (2006)
α-Synuclein pathology in the spinal cords of neurologically asymptomatic aged individuals
KJ Klos et al.
NEUROLOGY (2006)
The Parkinson's complex: Parkinsonism is just the tip of the iceberg
JW Langston
ANNALS OF NEUROLOGY (2006)
Gastric α-synuclein immunoreactive inclusions in Meissner's and Auerbach's plexuses in cases staged for Parkinson's disease-related brain pathology
H Braak et al.
NEUROSCIENCE LETTERS (2006)
Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB): Report of the Consortium on DLB International Workshop
Ian G. McKeith
JOURNAL OF ALZHEIMERS DISEASE (2006)
Epidemiology of Parkinson's disease
Lonneke M. L. de Lau et al.
LANCET NEUROLOGY (2006)
Diagnosis and management of dementia with Lewy bodies - Third report of the DLB consortium
IG McKeith et al.
NEUROLOGY (2005)
Effects of α-synuclein immunization in a mouse model of Parkinson's disease
E Masliah et al.
NEURON (2005)
Cardiac sympathetic denervation precedes neuronal loss in the sympathetic ganglia in Lewy body disease
S Orimo et al.
ACTA NEUROPATHOLOGICA (2005)
Parkinson's disease α-synuclein mutations exhibit defective axonal transport in cultured neurons
AR Saha et al.
JOURNAL OF CELL SCIENCE (2004)
The new mutation, E46K, of α-synuclein causes Parkinson and Lewy body dementia
JJ Zarranz et al.
ANNALS OF NEUROLOGY (2004)
α-synuclein locus duplication as a cause of familial Parkinson's disease
MC Chartier-Harlin et al.
LANCET (2004)
Causal relation between α-synuclein gene duplication and familial Parkinson's disease
P Ibáñez et al.
LANCET (2004)
Lewy body-related α-synucleinopathy in aging
Y Saito et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2004)
Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease
C Paisán-Ruíz et al.
NEURON (2004)
Mutations in LRRK2 cause autosomal-dominant Parkinsonism with pleomorphic pathology
A Zimprich et al.
NEURON (2004)
The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization
RM Canet-Avilés et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Hereditary early-onset Parkinson's disease caused by mutations in PINK1
EM Valente et al.
SCIENCE (2004)
α-synuclein locus triplication causes Parkinson's disease
AB Singleton et al.
SCIENCE (2003)
Dopaminergic neuronal loss and motor deficits in Caenorhabditis elegans overexpressing human α-synuclein
M Lakso et al.
JOURNAL OF NEUROCHEMISTRY (2003)
Staging of brain pathology related to sporadic Parkinson's disease
H Braak et al.
NEUROBIOLOGY OF AGING (2003)
Neuronal loss is greater in the locus coeruleus than nucleus basalis and substantia nigra in Alzheimer and Parkinson diseases
C Zarow et al.
ARCHIVES OF NEUROLOGY (2003)
Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism
V Bonifati et al.
SCIENCE (2003)
Morphogenesis of Lewy bodies: Dissimilar incorporation of alpha-synuclein, ubiquitin, and p62
E Kuusisto et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2003)
Microscopic analysis of polymerization dynamics with individual actin filaments
I Fujiwara et al.
NATURE CELL BIOLOGY (2002)
α-Synucleinopathy and selective dopaminergic neuron loss in a rat lentiviral-based model of Parkinson's disease
C Lo Bianco et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Neuronal α-synucleinopathy with severe movement disorder in mice expressing A53T human α-synuclein
BI Giasson et al.
NEURON (2002)
Chaperone suppression of α-synuclein toxicity in a Drosophila model for Parkinson's disease
PK Auluck et al.
SCIENCE (2002)
Lewy body pathology in Alzheimer's disease
PT Kotzbauer et al.
JOURNAL OF MOLECULAR NEUROSCIENCE (2001)
Deletion of the alpha-synuclein locus in a subpopulation of C57BL/6J inbred mice
Christian G. Specht et al.
BMC NEUROSCIENCE (2001)
Alpha-synuclein and neurodegenerative diseases
M Goedert
NATURE REVIEWS NEUROSCIENCE (2001)
Chronic systemic pesticide exposure reproduces features of Parkinson's disease
R Betarbet et al.
NATURE NEUROSCIENCE (2000)
Fiber diffraction of synthetic α-synuclein filaments shows amyloid-like cross-β conformation
LC Serpell et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
A Drosophila model of Parkinson's disease
MB Feany et al.
NATURE (2000)
Dopaminergic loss and inclusion body formation in α-synuclein mice:: Implications for neurodegenerative disorders
E Masliah et al.
SCIENCE (2000)
Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system
A Abeliovich et al.
NEURON (2000)
分享论文
