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TRANSPLANTATION Desensitization and transplantation for sensitized patients?

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NATURE REVIEWS NEPHROLOGY
卷 7, 期 12, 页码 682-683

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NATURE PUBLISHING GROUP
DOI: 10.1038/nrneph.2011.148

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For patients who undergo desensitization treatment to reduce or neutralize circulating donor-specific anti-HLA antibodies prior to transplantation, survival is lower than for unsensitized patients. However, a new study suggests that for sensitized patients, desensitization and transplantation might be better than remaining on dialysis or waiting for a compatible kidney transplant.

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