相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Glutamine metabolism links growth factor signaling to the regulation of autophagy
Kristan E. van der Vos et al.
AUTOPHAGY (2012)
MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB
Jose A. Martina et al.
AUTOPHAGY (2012)
Ragulator Is a GEF for the Rag GTPases that Signal Amino Acid Levels tomTORC1
Liron Bar-Peled et al.
CELL (2012)
mTOR Signaling in Growth Control and Disease
Mathieu Laplante et al.
CELL (2012)
Leucyl-tRNA Synthetase Is an Intracellular Leucine Sensor for the mTORC1-Signaling Pathway
Jung Min Han et al.
CELL (2012)
A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB
Carmine Settembre et al.
EMBO JOURNAL (2012)
Crystal Structure of the Gtr1pGTP-Gtr2pGDP Protein Complex Reveals Large Structural Rearrangements Triggered by GTP-to-GDP Conversion
Jae-Hee Jeong et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Structure-Activity Analysis of Niclosamide Reveals Potential Role for Cytoplasmic pH in Control of Mammalian Target of Rapamycin Complex 1 (mTORC1) Signaling
Bruno D. Fonseca et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
The Vam6 and Gtr1-Gtr2 pathway activates TORC1 in response to amino acids in fission yeast
Noelia Valbuena et al.
JOURNAL OF CELL SCIENCE (2012)
SH3BP4 Is a Negative Regulator of Amino Acid-Rag GTPase-mTORC1 Signaling
Young-Mi Kim et al.
MOLECULAR CELL (2012)
Leucyl-tRNA Synthetase Controls TORC1 via the EGO Complex
Gregory Bonfils et al.
MOLECULAR CELL (2012)
Glutaminolysis Activates Rag-mTORC1 Signaling
Raul V. Duran et al.
MOLECULAR CELL (2012)
Modulation of glutamine metabolism by the PI(3)K-PKB-FOXO network regulates autophagy
Kristan E. van der Vos et al.
NATURE CELL BIOLOGY (2012)
Ego3 Functions as a Homodimer to Mediate the Interaction between Gtr1-Gtr2 and Ego1 in the EGO Complex to Activate TORC1
Tianlong Zhang et al.
STRUCTURE (2012)
Autophagy: Renovation of Cells and Tissues
Noboru Mizushima et al.
CELL (2011)
Crystal structure of the Gtr1p-Gtr2p complex reveals new insights into the amino acid-induced TORC1 activation
Rui Gong et al.
GENES & DEVELOPMENT (2011)
Target of Rapamycin (TOR) in Nutrient Signaling and Growth Control
Robbie Loewith et al.
GENETICS (2011)
The TGF-β signaling modulators TRAP1/TGFBRAP1 and VPS39/Vam6/TLP are essential for early embryonic development
Sabine Messller et al.
IMMUNOBIOLOGY (2011)
Structural Characterization of HBXIP: The Protein That Interacts with the Anti-Apoptotic Protein Survivin and the Oncogenic Viral Protein HBx
I. Garcia-Saez et al.
JOURNAL OF MOLECULAR BIOLOGY (2011)
AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
Joungmok Kim et al.
NATURE CELL BIOLOGY (2011)
mTOR: from growth signal integration to cancer, diabetes and ageing
Roberto Zoncu et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2011)
Regulation of mTORC1 Signaling by pH
Aruna D. Balgi et al.
PLOS ONE (2011)
mTORC1 Senses Lysosomal Amino Acids Through an Inside-Out Mechanism That Requires the Vacuolar H+-ATPase
Roberto Zoncu et al.
SCIENCE (2011)
Arginine-induced stimulation of protein synthesis and survival in IPEC-J2 cells is mediated by mTOR but not nitric oxide
Caroline Bauchart-Thevret et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2010)
Ragulator-Rag Complex Targets mTORC1 to the Lysosomal Surface and Is Necessary for Its Activation by Amino Acids
Yasemin Sancak et al.
CELL (2010)
Regulation of mTORC1 by the Rab and Arf GTPases
Li Li et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Structural Conservation of Components in the Amino Acid Sensing Branch of the TOR Pathway in Yeast and Mammals
Konstantin Kogan et al.
JOURNAL OF MOLECULAR BIOLOGY (2010)
Amino acid regulation of TOR complex 1
Joseph Avruch et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2009)
Bidirectional Transport of Amino Acids Regulates mTOR and Autophagy
Paul Nicklin et al.
CELL (2009)
ULK1•ATG13•FIP200 Complex Mediates mTOR Signaling and Is Essential for Autophagy
Ian G. Ganley et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Nutrient-dependent mTORC1 Association with the ULK1-Atg13-FIP200 Complex Required for Autophagy
Nao Hosokawa et al.
MOLECULAR BIOLOGY OF THE CELL (2009)
ULK-Atg13-FIP200 Complexes Mediate mTOR Signaling to the Autophagy Machinery
Chang Hwa Jung et al.
MOLECULAR BIOLOGY OF THE CELL (2009)
The Vam6 GEF Controls TORC1 by Activating the EGO Complex
Matteo Binda et al.
MOLECULAR CELL (2009)
AMPK phosphorylation of raptor mediates a metabolic checkpoint
Dana M. Gwinn et al.
MOLECULAR CELL (2008)
Regulation of TORC1 by Rag GTPases in nutrient response
Eunjung Kim et al.
NATURE CELL BIOLOGY (2008)
The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1
Yasemin Sancak et al.
SCIENCE (2008)
Nitrogen availability and TOR regulate the Snf1 protein kinase in Saccharomyces cerevisiae
Marianna Orlova et al.
EUKARYOTIC CELL (2006)
Cell growth control: little eukaryotes make big contributions
C. De Virgilio et al.
ONCOGENE (2006)
TSC2 integrates Wnt and energy signals via a coordinated phosphorylation by AMPK and GSK3 to regulate cell growth
Ken Inoki et al.
CELL (2006)
Rheb binding to mammalian target of rapamycin (mTOR) is regulated by amino acid sufficiency
XM Long et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
The tuberous sclerosis protein TSC2 is not required for the regulation of the mammalian target of rapamycin by amino acids and certain cellular stresses
EM Smith et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Crystal structure of the p14/MP1 scaffolding complex flow a twin couple attaches mitogen-activated protein kinase signaling to late endosomes
R Kurzbauer et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
The structure of the MAPK scaffold, MP1, bound to its partner, p14
VV Lunin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
The vacuolar (H+)-atpases -: Nature's most versatile proton pumps
T Nishi et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2002)
Antagonistic controls of autophagy and glycogen accumulation by Snf1p, the yeast homolog of AMP-activated protein kinase, and the cyclin-dependent kinase Pho85p
Z Wang et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
Novel G proteins, Rag C and Rag D, interact with GTP-binding proteins, Rag A and Rag B
T Sekiguchi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
分享论文
