期刊
NATURE REVIEWS MOLECULAR CELL BIOLOGY
卷 13, 期 5, 页码 328-335出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/nrm3335
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资金
- Spanish Ministry of Science and Innovation (Instituto de Salud Carlos III)
- Spanish Ministry of Science and Innovation
- Pro-CNIC Foundation
- [SAF2011-25834]
- [ERC-2011-AdG 294340-GENTRIS]
An emerging concept is that cellular communication in mammals can be mediated by the exchange of genetic information, mainly in the form of microRNAs. This can occur when extracellular vesicles, such as exosomes, secreted by a donor cell are taken up by an acceptor cell. Transfer of genetic material can also occur through intimate membrane contacts between donor and acceptor cells. Specialized cell-cell contacts, such as synapses, have the potential to combine these modes of genetic transfer.
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