期刊
NATURE REVIEWS MOLECULAR CELL BIOLOGY
卷 10, 期 1, 页码 44-52出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/nrm2595
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- US Public Health Service [GM30997]
- NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM030997, R37GM030997] Funding Source: NIH RePORTER
Neurons that sense touch, sound and acceleration respond rapidly to specific mechanical signals. The proteins that transduce these signals and underlie these senses, however, are mostly unknown. Research over the past decade has suggested that members of three families of channel proteins are candidate transduction molecules. Current studies are directed towards characterizing these candidates, determining how they are mechanically gated and discovering new molecules that are involved in mechanical sensing.
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