期刊
NATURE REVIEWS MOLECULAR CELL BIOLOGY
卷 10, 期 5, 页码 344-352出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/nrm2668
关键词
-
类别
资金
- National Institutes of Health [HL36783, HL49907, DK51767]
- NATIONAL HEART, LUNG, AND BLOOD INSTITUTE [R37HL049907, R01HL036783, R01HL049907] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES [R01DK051767] Funding Source: NIH RePORTER
The incessant traffic of ions across cell membranes is controlled by two kinds of border guards: ion channels and ion pumps. Open channels let selected ions diffuse rapidly down electrical and concentration gradients, whereas ion pumps labour tirelessly to maintain the gradients by consuming energy to slowly move ions thermodynamically uphill. Because of the diametrically opposed tasks and the divergent speeds of channels and pumps, they have traditionally been viewed as completely different entities, as alike as chalk and cheese. But new structural and mechanistic information about both of these classes of molecular machines challenges this comfortable separation and forces its re-evaluation.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据