期刊
NATURE REVIEWS MOLECULAR CELL BIOLOGY
卷 10, 期 11, 页码 765-777出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/nrm2782
关键词
-
类别
资金
- NIGMS NIH HHS [R01 GM070862-05, R01 GM070862] Funding Source: Medline
Kinesins are a family of molecular motors that use the energy of ATP hydrolysis to move along the surface of, or destabilize, microtubule filaments. Much progress has been made in understanding the mechanics and functions of the kinesin motors that play important parts in cell division, cell motility, intracellular trafficking and ciliary function. How kinesins are regulated in cells to ensure the temporal and spatial fidelity of their microtubule-based activities is less well understood. Recent work has revealed molecular mechanisms that control kinesin autoinhibition and subsequent activation, binding to cargos and microtubule tracks, and localization at specific sites of action.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据