期刊
NATURE REVIEWS MOLECULAR CELL BIOLOGY
卷 11, 期 1, 页码 50-61出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/nrm2820
关键词
-
类别
资金
- Heart and Stroke Foundation of Canada
- Kidney Foundation
- Canadian Institutes of Health Research
Protons dictate the charge and structure of macromolecules and are used as energy currency by eukaryotic cells. The unique function of individual organelles therefore depends on the establishment and stringent maintenance of a distinct pH. This, in turn, requires a means to sense the prevailing pH and to respond to deviations from the norm with effective mechanisms to transport, produce or consume proton equivalents. A dynamic, finely tuned balance between proton-extruding and proton-importing processes underlies pH homeostasis not only in the cytosol, but in other cellular compartments as well.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据