期刊
NATURE REVIEWS MOLECULAR CELL BIOLOGY
卷 10, 期 2, 页码 148-155出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/nrm2617
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Most eukaryotic proteins are secreted through the conventional endoplasmic reticulum (ER)-Golgi secretory pathway. However, cytoplasmic, nuclear and signal-peptide- containing proteins have been shown to reach the cell surface by non-conventional transport pathways. the mechanisms and molecular components of unconventional protein secretion are beginning to emerge, including a role for caspase 1 and for the peripheral Golgi protein GRASP, which could function as a plasma membrane tether for membrane compartments during specific stages of development.
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