期刊
NATURE REVIEWS MICROBIOLOGY
卷 11, 期 6, 页码 400-411出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/nrmicro3015
关键词
-
类别
资金
- UK Medical Research Council
- University of Glasgow, UK
- European Commission [321703]
- Medical Research Council [G0801822, MC_UU_12014/4, MC_UU_12014/5, MC_UP_A550_1030, MC_U130169966] Funding Source: researchfish
- MRC [MC_UU_12014/5, MC_UU_12014/4, MC_UP_A550_1030, MC_U130169966, G0801822] Funding Source: UKRI
Post-translational modification by members of the small ubiquitin-like modifier (SUMO) family of proteins is important for the regulation of many cellular proteins and pathways. As obligate parasites, viruses must engage with the host cell throughout their replication cycles, and it is therefore unsurprising that there are many examples of interplay between viral proteins and the host sumoylation system. This article reviews recent advances in this field, summarizing information on sumoylated viral proteins, the varied ways in which viruses engage with SUMO-related pathways, and the consequences of these interactions for viral replication and engagement with innate and intrinsic immunity.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据