期刊
NATURE REVIEWS MICROBIOLOGY
卷 10, 期 3, 页码 165-177出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/nrmicro2673
关键词
-
类别
资金
- Intramural Research Program of the US National Institutes of Allergy and Infectious Diseases (NIAID), National Institutes of Health [Z01 AI000788]
- NIAID
- Virginia Tech Carilion Research Institute (Roanoke, USA)
Viral replication is rapid and robust, but it is far from a chaotic process. Instead, successful production of infectious progeny requires that events occur in the correct place and at the correct time. Rotaviruses (segmented double-stranded RNA viruses of the Reoviridae family) seem to govern their replication through ordered disassembly and assembly of a triple-layered icosahedral capsid. In recent years, high-resolution structural data have provided unprecedented insight into these events. In this Review, we explore the current understanding of rotavirus replication and how it compares to replication of other Reoviridae family members.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据