期刊
NATURE REVIEWS GENETICS
卷 15, 期 2, 页码 69-81出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/nrg3623
关键词
-
资金
- Intramural NIH HHS [Z01 BC005450-24] Funding Source: Medline
The interaction of regulatory proteins with the complex nucleoprotein structures that are found in mammalian cells involves chromatin reorganization at multiple levels. Mechanisms that support these transitions are complex on many timescales, which range from milliseconds to minutes or hours. In this Review, we discuss emerging concepts regarding the function of regulatory elements in living cells. We also explore the involvement of these dynamic and stochastic processes in the evolution of fluctuating transcriptional activity states that are now commonly reported in eukaryotic systems.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据