期刊
NATURE REVIEWS GENETICS
卷 11, 期 6, 页码 446-450出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/nrg2809
关键词
-
资金
- Wellcome Trust
- US National Institutes of Health [R01s LM009012, LM010098, AI59694]
Although recent genome-wide studies have provided valuable insights into the genetic basis of human disease, they have explained relatively little of the heritability of most complex traits, and the variants identified through these studies have small effect sizes. This has led to the important and hotly debated issue of where the 'missing heritability' of complex diseases might be found. Here, seven leading geneticists offer their opinion about where this heritability is likely to lie, what this could tell us about the underlying genetic architecture of common diseases and how this could inform research strategies for uncovering genetic risk factors.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据