期刊
NATURE REVIEWS GENETICS
卷 11, 期 12, 页码 855-866出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/nrg2897
关键词
-
资金
- National Institutes of Health
- National Science Foundation, USA
- Research Council of Norway
A key goal of biology is to understand phenotypic characteristics, such as health, disease and evolutionary fitness. Phenotypic variation is produced through a complex web of interactions between genotype and environment, and such a 'genotype-phenotype' map is inaccessible without the detailed phenotypic data that allow these interactions to be studied. Despite this need, our ability to characterize phenomes - the full set of phenotypes of an individual - lags behind our ability to characterize genomes. Phenomics should be recognized and pursued as an independent discipline to enable the development and adoption of high-throughput and high-dimensional phenotyping.
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