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Gut microbiome, microbial metabolites and the development of NAFLD

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NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY
卷 15, 期 12, 页码 719-720

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NATURE PORTFOLIO
DOI: 10.1038/s41575-018-0058-x

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New findings show that a gut microbiome signature derived from metagenomic and phenomic data can accurately predict nonalcoholic fatty liver disease (NAFLD) in obese women. The data highlight a role for phenylacetic acid, a microbial product of aromatic amino acid metabolism, in the cross-talk between the gut microbiome and the host hepatic phenotype.

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