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Cytosolic FoxO1 is essential for the induction of autophagy and tumour suppressor activity
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Promotion of direct reprogramming by transformation-deficient Myc
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The Ectopic Expression of Pax4 in the Mouse Pancreas Converts Progenitor Cells into α and Subsequently β Cells
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Autophagy in human type 2 diabetes pancreatic beta cells
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Regulation of Pancreatic Juxtaductal Endocrine Cell Formation by FoxO1
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Autophagy Is Important in Islet Homeostasis and Compensatory Increase of Beta Cell Mass in Response to High-Fat Diet
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Inhibition of Foxol protects pancreatic islet β-cells against fatty acid and endoplasmic reticulum stress-induced apoptosis
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Pancreatic β-cell mass in European subjects with type 2 diabetes
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Islet amyloid in type 2 diabetes, and the toxic oligomer hypothesis
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pVHL is a regulator of glucose metabolism and insulin secretion in pancreatic β cells
Jens Zehetner et al.
GENES & DEVELOPMENT (2008)
Increased interleukin (IL)-1β messenger ribonucleic acid expression in β-cells of individuals with type 2 diabetes and regulation of IL-1β in human islets by glucose and autostimulation
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JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2008)
Arginine Methylation of FOXO Transcription Factors Inhibits Their Phosphorylation by Akt
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Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus
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Association of TCF7L2 polymorphisms with susceptibility to type 2 diabetes in 4,087 Japanese subjects
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The endoplasmic reticulum in pancreatic beta cells of type 2 diabetes patients
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The replication of β cells in normal physiology, in disease and for therapy
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A Foxo/Notch pathway controls myogenic differentiation and fiber type specification
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Increased number of islet-associated macrophages in type 2 diabetes
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Role of FoxO proteins in pancreatic β cells
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Membrane interaction of islet amyloid polypeptide
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Embryonic endocrine pancreas and mature β cells acquire α and PP cell phenotypes upon Arx misexpression
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Expansion of adult β-cell mass in response to increased metabolic demand is dependent on HNF-4α
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Glucokinase and IRS-2 are required for compensatory beta cell hyperplasia in response to high-fat diet-induced insulin resistance
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Autophagy is activated for cell survival after endoplasmic reticulum stress
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CDK2-dependent phosphorylation of FOXO1 as an apoptotic response to DNA damage
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p16INK4a induces an age-dependent decline in islet regenerative potential
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Total insulin and IGF-I resistance in pancreatic β cells causes overt diabetes
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Forkhead protein FoxO1 mediates Agrp-dependent effects of leptin on food intake
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Ablation of PDK1 in pancreatic β cells induces diabetes as a result of loss of β cell mass
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Autophagic programmed cell death by selective catalase degradation
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Role of the forkhead protein FoxO1 in β cell compensation to insulin resistance
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Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes
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The forkhead transcription factor foxo1 bridges the JNK pathway and the transcription factor PDX-1 through its intracellular translocation
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Involvement of Foxo transcription factors in angiogenesis and postnatal neovascularization
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Essential role of endothelial Notch1 in angiogenesis
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Functional and molecular defects of pancreatic islets in human type 2 diabetes
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Deletion of Cdkn1b ameliorates hyperglycemia by maintaining compensatory hyperinsulinemia in diabetic mice
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IκB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a
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CELL (2004)
Dual roles for the notch target gene Hes-1 in the differentiation of 3T3-L1 preadipocytes
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Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase
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Disruption of forkhead transcription factor (FOXO) family members in mice reveals their functional diversification
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Mammalian SIRT1 represses forkhead transcription factors
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