4.6 Editorial Material

DIABETES Immunotherapy for T1DI-still not there yet

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NATURE REVIEWS ENDOCRINOLOGY
卷 9, 期 12, 页码 697-698

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NATURE PUBLISHING GROUP
DOI: 10.1038/nrendo.2013.221

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Alefacept, a fusion protein approved for psoriasis, has been Walled in patients with new-onset type 1 diabetes mellitus. However, the withdrawal of the drug from the US market and the unmet primary end point do not raise hope for this drug, even though some secondary end points were met and the study highlighted interesting immunological efficacy.

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