相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Safety and efficacy of linagliptin as add-on therapy to metformin in patients with type 2 diabetes: a randomized, double-blind, placebo-controlled study
M. -R. Taskinen et al.
DIABETES OBESITY & METABOLISM (2011)
Hyperphagia and Increased Fat Accumulation in Two Models of Chronic CNS Glucagon-Like Peptide-1 Loss of Function
Jason G. Barrera et al.
JOURNAL OF NEUROSCIENCE (2011)
Incretin-Based Therapies: Review of Current Clinical Trial Data
Anne Peters
AMERICAN JOURNAL OF MEDICINE (2010)
Exendin-4 increases blood glucose levels acutely in rats by activation of the sympathetic nervous system
Diego Perez-Tilve et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2010)
Lesions of area postrema and subfornical organ alter exendin-4-induced brain activation without preventing the hypophagic effect of the GLP-1 receptor agonist
Elena-Dana Baraboi et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2010)
Exenatide reduces food intake and activates the enteric nervous system of the gastrointestinal tract and the dorsal vagal complex of the hindbrain in the rat by a GLP-1 receptor
Martha C. Washington et al.
BRAIN RESEARCH (2010)
Leptin Directly Depolarizes Preproglucagon Neurons in the Nucleus Tractus Solitarius Electrical Properties of Glucagon-Like Peptide 1 Neurons
Kazunari Hisadome et al.
DIABETES (2010)
Twelve weeks treatment with the DPP-4 inhibitor, sitagliptin, prevents degradation of peptide YY and improves glucose and non-glucose induced insulin secretion in patients with type 2 diabetes mellitus
K. Aaboe et al.
DIABETES OBESITY & METABOLISM (2010)
Meal-Anticipatory Glucagon-Like Peptide-1 Secretion in Rats
Torsten P. Vahl et al.
ENDOCRINOLOGY (2010)
Molecular mechanisms underlying nutrient-stimulated incretin secretion
Helen E. Parker et al.
EXPERT REVIEWS IN MOLECULAR MEDICINE (2010)
Sensitivity to the satiating effects of exendin 4 is decreased in obesity-prone Osborne-Mendel rats compared to obesity-resistant S5B/PI rats
S. D. Primeaux et al.
INTERNATIONAL JOURNAL OF OBESITY (2010)
Secretion and Dipeptidyl Peptidase-4-Mediated Metabolism of Incretin Hormones after a Mixed Meal or Glucose Ingestion in Obese Compared to Lean, Nondiabetic Men
Richard D. Carr et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2010)
Hindbrain leptin receptor stimulation enhances the anorexic response to cholecystokinin
Diana L. Williams et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2009)
Immune challenge and satiety-related activation of both distinct and overlapping neuronal populations in the brainstem indicate parallel pathways for viscerosensory signaling
Ronald P. A. Gaykema et al.
BRAIN RESEARCH (2009)
Differences in the Central Anorectic Effects of Glucagon-Like Peptide-1 and Exendin-4 in Rats
Jason G. Barrera et al.
DIABETES (2009)
Intrameal Hepatic Portal and Intraperitoneal Infusions of Glucagon-Like Peptide-1 Reduce Spontaneous Meal Size in the Rat via Different Mechanisms
Elisabeth B. Ruettimann et al.
ENDOCRINOLOGY (2009)
Endogenous Hindbrain Glucagon-Like Peptide-1 Receptor Activation Contributes to the Control of Food Intake by Mediating Gastric Satiation Signaling
Matthew R. Hayes et al.
ENDOCRINOLOGY (2009)
Evidence that Intestinal Glucagon-Like Peptide-1 Plays a Physiological Role in Satiety
Diana L. Williams et al.
ENDOCRINOLOGY (2009)
Direct Control of Peripheral Lipid Deposition by CNS GLP-1 Receptor Signaling Is Mediated by the Sympathetic Nervous System and Blunted in Diet-Induced Obesity
Ruben Nogueiras et al.
JOURNAL OF NEUROSCIENCE (2009)
Effects of liraglutide in the treatment of obesity: a randomised, double-blind, placebo-controlled study
Arne Astrup et al.
LANCET (2009)
Liraglutide once a day versus exenatide twice a day for type 2 diabetes: a 26-week randomised, parallel-group, multinational, open-label trial (LEAD-6)
John B. Buse et al.
LANCET (2009)
Receptor-mediated activation of gastric vagal afferents by glucagon-like peptide-1 in the rat
V. Bucinskaite et al.
NEUROGASTROENTEROLOGY AND MOTILITY (2009)
Do Incretins Play a Role in the Remission of Type 2 Diabetes after Gastric Bypass Surgery: What are the Evidence?
Mousumi Bose et al.
OBESITY SURGERY (2009)
Glucocorticoid regulation of preproglucagon transcription and RNA stability during stress
Rong Zhang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
The effects of GLP-1 infusion in the hepatic portal region on food intake
Dong-Hoon Kim et al.
REGULATORY PEPTIDES (2009)
Upregulation of the brainstem preproglucagon system in the obese Zucker rat
Niels Vrang et al.
BRAIN RESEARCH (2008)
Brain glucagon-like peptide-1 regulates arterial blood flow, heart rate, and insulin sensitivity
Cendrine Cabou et al.
DIABETES (2008)
Role of central nervous system glueagon-like peptide-1 reeeptors in enterie glueose sensing
Claude Knauf et al.
DIABETES (2008)
Arcuate glucagon-like peptide 1 receptors regulate glucose homeostasis but not food intake
Darleen A. Sandoval et al.
DIABETES (2008)
Efficacy and Safety of the Dipeptidyl Peptidase-4 Inhibitor Alogliptin in Patients With Type 2 Diabetes and Inadequate Glycemic Control A randomized, double-blind, placebo-controlled study
Ralph A. DeFronzo et al.
DIABETES CARE (2008)
Glucose-lowering activity of the dipeptidyl peptidase-4 inhibitor saxagliptin in drug-naive patients with type 2 diabetes
J. Rosenstock et al.
DIABETES OBESITY & METABOLISM (2008)
Caudal brainstem processing is sufficient for behavioral, sympathetic, and parasympathetic responses driven by peripheral and hindbrain glucagon-like-peptide-1 receptor stimulation
Matthew R. Hayes et al.
ENDOCRINOLOGY (2008)
Divergent leptin signaling in proglucagon neurons of the nucleus of the solitary tract in mice and rats
Lihong Huo et al.
ENDOCRINOLOGY (2008)
Brain glucagon-like peptide 1 signaling controls the onset of high-fat diet-induced insulin resistance and reduces energy expenditure
Claude Knauf et al.
ENDOCRINOLOGY (2008)
An albumin-exendin-4 conjugate engages central and peripheral circuits regulating murine energy and glucose Homeostasis
Laurie L. Baggio et al.
GASTROENTEROLOGY (2008)
Separate impact of obesity and glucose tolerance on the incretin effect in normal subjects and type 2 diabetic patients
Elza Muscelli et al.
DIABETES (2008)
Differential antidiabetic efficacy of incretin agonists versus DPP-4 inhibition in high fat-fed mice
Benjamin J. Lamont et al.
DIABETES (2008)
Glucagon-like peptide-1 modulates synaptic transmission to identified pancreas-projecting vagal motoneurons
Shuxia Wan et al.
PEPTIDES (2007)
Glucagon-like peptide-1 (GLP-1) receptors expressed on nerve terminals in the portal vein mediate the effects of endogenous GLP-1 on glucose tolerance in rats
Torsten P. Vahl et al.
ENDOCRINOLOGY (2007)
The physiology of glucagon-like peptide 1
Jens Juul Holst
PHYSIOLOGICAL REVIEWS (2007)
The GLP-1 agonist exendin-4 reduces food intake in nonhuman primates through changes in meal size
Karen A. Scott et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2007)
Characterization of brainstem preproglucagon projections to the paraventricular and dorsomedial hypothalamic nuclei
Niels Vrang et al.
BRAIN RESEARCH (2007)
Biology of incretins: GLP-1 and GIP
Laurie L. Baggio et al.
GASTROENTEROLOGY (2007)
Glucagon like peptide-1 accelerates colonic transit via central CRF and peripheral vagal pathways in conscious rats
Yukiomi Nakade et al.
AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL (2007)
Glucagon-like peptide-1 excites pancreas-projecting preganglionic vagal motoneurons
S. Wan et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2007)
Extrapancreatic incretin receptors modulate glucose homeostasis, body weight, and energy expenditure
Tanya Hansotia et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Liraglutide, a long-acting human glucagon-like peptide-1 analog, given as monotherapy significantly improves glycemic control and lowers body weight without risk of hypoglycemia in patients with type 2 diabetes
Tina Vilsboll et al.
DIABETES CARE (2007)
Liraglutide, a long-acting glucagon-like peptide-1 analog, reduces body weight and food intake in obese candy-fed rats, whereas a dipeptidyl peptidase-IV inhibitor, vildagliptin, does not
Kirsten Raun et al.
DIABETES (2007)
Leptin regulation of the anorexic response to glucagon-like peptide-1 receptor stimulation
Diana L. Williams et al.
DIABETES (2006)
Efficacy and safety of the dipeptidyl peptidase-4 inhibitor sitagliptin as monotherapy in patients with type 2 diabetes mellitus
I. Raz et al.
DIABETOLOGIA (2006)
Central glucagon like peptide-1 delays solid gastric emptying via central CRF and peripheral sympathetic pathway in rats
Yukiomi Nakade et al.
BRAIN RESEARCH (2006)
Antiobesity action of peripheral exenatide (exendin-4) in rodents: effects on food intake, body weight, metabolic status and side-effect measures
C. M. Mack et al.
INTERNATIONAL JOURNAL OF OBESITY (2006)
Twelve-week monotherapy with the DPP-4 inhibitor vildagliptin improves glycemic control in subjects with type 2 diabetes
R. E. Pratley et al.
HORMONE AND METABOLIC RESEARCH (2006)
Brain glucagon-like peptide-1 increases insulin secretion and muscle insulin resistance to favor hepatic glycogen storage
C Knauf et al.
JOURNAL OF CLINICAL INVESTIGATION (2005)
Peripheral exendin-4 and peptide YY3-36 synergistically reduce food intake through different mechanisms in mice
T Talsania et al.
ENDOCRINOLOGY (2005)
The inhibitory effects of peripheral administration of peptide YY3-36 and glucagon-like peptide-1 on food intake are attenuated by ablation of the vagal-brainstem-hypothalamic pathway
CR Abbott et al.
BRAIN RESEARCH (2005)
Effects of exenatide (exendin-4) on glycemic control over 30 weeks in patients with type 2 diabetes treated with metformin and a sulfonylurea
DM Kendall et al.
DIABETES CARE (2005)
Effects of exenatide (exendin-4) on glycemic control and weight over 30 weeks in metformin-treated patients with type 2 diabetes
RA DeFronzo et al.
DIABETES CARE (2005)
Leptin action in the forebrain regulates the hindbrain response to satiety signals
GJ Morton et al.
JOURNAL OF CLINICAL INVESTIGATION (2005)
The role of central glucagon-like peptide-1 in mediating the effects of visceral illness: Differential effects in rats and mice
JL Lachey et al.
ENDOCRINOLOGY (2005)
Gastrointestinal satiety signals - II. Cholecystokinin
TH Moran et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2004)
Receptor gene expression of glucagon-like peptide-1, but not glucose-dependent insulinotropic polypeptide, in rat nodose ganglion cells
A Nakagawa et al.
AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL (2004)
A recombinant human glucagon-like peptide (GLP)-1-albumin protein (Albugon) mimics peptidergic activation of GLP-1 receptor-dependent pathways coupled with satiety, gastrointestinal motility, and glucose homeostasis
LL Baggio et al.
DIABETES (2004)
Effects of exenatide (exendin-4) on glycemic control over 30 weeks in sulfonylurea-treated patients with type 2 diabetes
JB Buse et al.
DIABETES CARE (2004)
Attenuation of lipopolysaccharide anorexia by antagonism of caudal brain stem but not forebrain GLP-1-R
HJ Grill et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2004)
Gastric distension induces c-Fos in medullary GLP-1/2-containing neurons
N Vrang et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2003)
Incretin secretion in relation to meal size and body weight in healthy subjects and people with type 1 and type 2 diabetes mellitus
T Vilsboll et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2003)
Peptides that regulate food intake - Glucagon-like peptide 1-(7-36) amide acts at lateral and medial hypothalamic sites to suppress feeding in rats
RR Schick et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2003)
Entry of exendin-4 into brain is rapid but may be limited at high doses
AJ Kastin et al.
INTERNATIONAL JOURNAL OF OBESITY (2003)
Role of leptin in the regulation of glucagon-like peptide-1 secretion
Y Anini et al.
DIABETES (2003)
Endoproteolysis by isolated membrane peptidases reveal metabolic stability of glucagon-like peptide-1 analogs, exendins-3 and-4
A Thum et al.
EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES (2002)
A meta-analysis of the effect of glucagon-like peptide-1 (7-36) amide on ad libitum energy intake in humans
C Verdich et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2001)
The effect of physiological levels of glucagon-like peptide-1 on appetite, gastric emptying, energy and substrate metabolism in obesity
A Flint et al.
INTERNATIONAL JOURNAL OF OBESITY (2001)
Is parental control over children's eating associated with childhood obesity? Results from a population-based sample of third graders
TN Robinson et al.
OBESITY RESEARCH (2001)
Reduced postprandial concentrations of intact biologically active gluccagon-like peptide 1 in type 2 diabetic patients
T Vilsboll et al.
DIABETES (2001)
Antagonism of central glucagon-like peptide-1 receptors enhances lipopolysaccharide-induced fever
L Rinaman et al.
AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL (2000)
Leptin deficiency induced by fasting impairs the satiety response to cholecystokinin
JE McMinn et al.
ENDOCRINOLOGY (2000)
Central exendin-4 infusion reduces body weight without altering plasma leptin in (fa/fa) Zucker rats
KA Al-Barazanji et al.
OBESITY RESEARCH (2000)
Exendin-4 decelerates food intake, weight gain, and fat deposition in Zucker rats
M Szayna et al.
ENDOCRINOLOGY (2000)
Peripheral versus central effects of glucagon-like peptide-1 receptor agonists on satiety and body weight loss in Zucker obese rats
FR de Fonseca et al.
METABOLISM-CLINICAL AND EXPERIMENTAL (2000)
Effect of leptin on hypothalamic GLP-1 peptide and brain-stem pre-proglucagon mRNA
AP Goldstone et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2000)
分享论文
