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Efficacy and immunomodulatory actions of ONO-4641, a novel selective agonist for sphingosine 1-phosphate receptors 1 and 5, in preclinical models of multiple sclerosis
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CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2013)
Genetic elevation of Sphingosine 1-phosphate suppresses dystrophic muscle phenotypes in Drosophila
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Sphingosine analogue drug FTY720 targets I2PP2A/SET and mediates lung tumour suppression via activation of PP2A-RIPK1-dependent necroptosis
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EMBO MOLECULAR MEDICINE (2013)
Spns2, a transporter of phosphorylated sphingoid bases, regulates their blood and lymph levels, and the lymphatic network
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FASEB JOURNAL (2013)
A specific sphingosine kinase 1 inhibitor attenuates airway hyperresponsiveness and inflammation in a mast cell-dependent murine model of allergic asthma
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JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2013)
Sphingosine kinase/sphingosine 1-phosphate (S1P)/S1P receptor axis is involved in liver fibrosis-associated angiogenesis
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JOURNAL OF HEPATOLOGY (2013)
Sphingosine-1-phosphate receptor 1 in classical Hodgkin lymphoma: assessment of expression and role in cell migration
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Fingolimod treatment in multiple sclerosis leads to increased macular volume
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Sphingosine 1-Phosphate Mediates Hyperalgesia via a Neutrophil-Dependent Mechanism
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PLOS ONE (2013)
Sphingosine-1-phosphate-mediated osteoclast precursor monocyte migration is a critical point of control in antibone-resorptive action of active vitamin D
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Fingolimod Therapy for Multiple Sclerosis
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Molecular Basis of Sphingosine Kinase 1 Substrate Recognition and Catalysis
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Sphingosine-1-Phosphate Receptor-3 Is a Novel Biomarker in Acute Lung Injury
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AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2012)
Sphingosine-1-Phosphate and Lymphocyte Egress from Lymphoid Organs
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ANNUAL REVIEW OF IMMUNOLOGY, VOL 30 (2012)
Evidence for a link between histone deacetylation and Ca2+ homoeostasis in sphingosine-1-phosphate lyase-deficient fibroblasts
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BIOCHEMICAL JOURNAL (2012)
Sphingosine kinase type 2 inhibition elevates circulating sphingosine 1-phosphate
Yugesh Kharel et al.
BIOCHEMICAL JOURNAL (2012)
Modulation of cellular S1P levels with a novel, potent and specific inhibitor of sphingosine kinase-1
Mark E. Schnute et al.
BIOCHEMICAL JOURNAL (2012)
S1PR1 is an effective target to block STAT3 signaling in activated B cell-like diffuse large B-cell lymphoma
Yong Liu et al.
BLOOD (2012)
The selective sphingosine 1-phosphate receptor modulator BAF312 redirects lymphocyte distribution and has species-specific effects on heart rate
P. Gergely et al.
BRITISH JOURNAL OF PHARMACOLOGY (2012)
S1PR1-STAT3 Signaling Is Crucial for Myeloid Cell Colonization at Future Metastatic Sites
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CANCER CELL (2012)
Sphingosine-1-Phosphate Produced by Sphingosine Kinase 1 Promotes Breast Cancer Progression by Stimulating Angiogenesis and Lymphangiogenesis
Masayuki Nagahashi et al.
CANCER RESEARCH (2012)
Mixed Lineage Kinase Domain-like Protein Mediates Necrosis Signaling Downstream of RIP3 Kinase
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CELL (2012)
The Mitochondrial Phosphatase PGAM5 Functions at the Convergence Point of Multiple Necrotic Death Pathways
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CELL (2012)
Sphingolipid Metabolism Cooperates with BAK and BAX to Promote the Mitochondrial Pathway of Apoptosis
Jerry E. Chipuk et al.
CELL (2012)
A Potent and Selective S1P1 Antagonist with Efficacy in Experimental Autoimmune Encephalomyelitis
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CHEMISTRY & BIOLOGY (2012)
S1P1 inhibits sprouting angiogenesis during vascular development
Adi Ben Shoham et al.
DEVELOPMENT (2012)
The Sphingosine-1-Phosphate Receptor S1PR1 Restricts Sprouting Angiogenesis by Regulating the Interplay between VE-Cadherin and VEGFR2
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DEVELOPMENTAL CELL (2012)
Flow-Regulated Endothelial S1P Receptor-1 Signaling Sustains Vascular Development
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DEVELOPMENTAL CELL (2012)
Communication between host organism and cancer cells is transduced by systemic sphingosine kinase 1/sphingosine 1-phosphate signalling to regulate tumour metastasis
Suriyan Ponnusamy et al.
EMBO MOLECULAR MEDICINE (2012)
The sphingosine-1-phosphate transporter Spns2 expressed on endothelial cells regulates lymphocyte trafficking in mice
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JOURNAL OF CLINICAL INVESTIGATION (2012)
Amelioration of Collagen-Induced Arthritis by a Novel S1P1 Antagonist with Immunomodulatory Activities
Yasuyuki Fujii et al.
JOURNAL OF IMMUNOLOGY (2012)
A Sphingosine-1-Phosphate Receptor 1-Directed Agonist Reduces Central Nervous System Inflammation in a Plasmacytoid Dendritic Cell-Dependent Manner
Georgina Galicia-Rosas et al.
JOURNAL OF IMMUNOLOGY (2012)
The Sjogren-Larsson Syndrome Gene Encodes a Hexadecenal Dehydrogenase of the Sphingosine 1-Phosphate Degradation Pathway
Kanae Nakahara et al.
MOLECULAR CELL (2012)
Sphingosine-1-Phosphate Enhances Satellite Cell Activation in Dystrophic Muscles through a S1PR2/STAT3 Signaling Pathway
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PLOS ONE (2012)
Mouse SPNS2 Functions as a Sphingosine-1-Phosphate Transporter in Vascular Endothelial Cells
Yu Hisano et al.
PLOS ONE (2012)
In Vitro and In Vivo Antagonism of a G Protein-Coupled Receptor (S1P3) with a Novel Blocking Monoclonal Antibody
Greg L. Harris et al.
PLOS ONE (2012)
Inhibition of Sphingosine Kinase-2 Suppresses Inflammation and Attenuates Graft Injury after Liver Transplantation in Rats
Qinlong Liu et al.
PLOS ONE (2012)
Characterization of Isoenzyme-Selective Inhibitors of Human Sphingosine Kinases
Peng Gao et al.
PLOS ONE (2012)
Crystal Structure of a Lipid G Protein-Coupled Receptor
Michael A. Hanson et al.
SCIENCE (2012)
Prevention of GVHD and graft rejection by a new S1P receptor agonist, W-061, in rat small bowel transplantation
Jinghai Song et al.
TRANSPLANT IMMUNOLOGY (2012)
Sphingosine-1-phosphate signaling and its role in disease
Michael Maceyka et al.
TRENDS IN CELL BIOLOGY (2012)
Effect of sphingosine 1-phosphate (S1P) receptor agonists FTY720 and CYM5442 on atherosclerosis development in LDL receptor deficient (LDL-R-/-) mice
Francesco Poti et al.
VASCULAR PHARMACOLOGY (2012)
The Transporter Spns2 Is Required for Secretion of Lymph but Not Plasma Sphingosine-1-Phosphate
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CELL REPORTS (2012)
Sphingosine 1-phosphate receptors and sphingosine kinase 1: novel biomarkers for clinical prognosis in breast, prostate, and hematological cancers
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FRONTIERS IN ONCOLOGY (2012)
S1P1 Receptor Modulation with Cyclical Recovery from Lymphopenia Ameliorates Mouse Model of Multiple Sclerosis
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MOLECULAR PHARMACOLOGY (2012)
Sphingosine-1-Phosphate Receptor-2 Function in Myeloid Cells Regulates Vascular Inflammation and Atherosclerosis
Athanasia Skoura et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2011)
A novel role for mitochondrial sphingosine-1-phosphate produced by sphingosine kinase-2 in PTP-mediated cell survival during cardioprotection
Ludovic Gomez et al.
BASIC RESEARCH IN CARDIOLOGY (2011)
Sphingosine kinase type 1 inhibition reveals rapid turnover of circulating sphingosine 1-phosphate
Yugesh Kharel et al.
BIOCHEMICAL JOURNAL (2011)
SAR analysis of innovative selective small molecule antagonists of sphingosine-1-phosphate 4 (S1P4) receptor
Mariangela Urbano et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2011)
Sphingosine Kinase Inhibitors and Cancer: Seeking the Golden Sword of Hercules
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CANCER RESEARCH (2011)
STAT3 Inhibition Is a Therapeutic Strategy for ABC-like Diffuse Large B-Cell Lymphoma
Anna Scuto et al.
CANCER RESEARCH (2011)
Endothelial Cells Are Central Orchestrators of Cytokine Amplification during Influenza Virus Infection
John R. Teijaro et al.
CELL (2011)
A Phase I Clinical Trial of Safingol in Combination with Cisplatin in Advanced Solid Tumors
Mark A. Dickson et al.
CLINICAL CANCER RESEARCH (2011)
Sphingosine-1-phospate receptor 4 (S1P4) deficiency profoundly affects dendritic cell function and TH17-cell differentiation in a murine model
Tobias Schulze et al.
FASEB JOURNAL (2011)
Sphingosine-1-phosphate produced by sphingosine kinase 2 in mitochondria interacts with prohibitin 2 to regulate complex IV assembly and respiration
Graham M. Strub et al.
FASEB JOURNAL (2011)
The sphingosine-1-phosphate receptor-1 antagonist, W146, causes early and short-lasting peripheral blood lymphopenia in mice
Gema Tarrason et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2011)
Sphingosine-1-phosphate Lyase Deficiency Produces a Pro-inflammatory Response While Impairing Neutrophil Trafficking
Maria L. Allende et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Lipid phosphate phosphatase 3 enables efficient thymic egress
Beatrice Breart et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2011)
Pharmacological inhibition of sphingosine kinase isoforms alters estrogen receptor signaling in human breast cancer
James W. Antoon et al.
JOURNAL OF MOLECULAR ENDOCRINOLOGY (2011)
BACE1 Activity Is Modulated by Cell-Associated Sphingosine-1-Phosphate
Nobumasa Takasugi et al.
JOURNAL OF NEUROSCIENCE (2011)
The Selective Sphingosine 1-Phosphate Receptor 1 Agonist Ponesimod Protects against Lymphocyte-Mediated Tissue Inflammation
Luca Piali et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2011)
Chronic sphingosine 1-phosphate 1 receptor activation attenuates early-stage diabetic nephropathy independent of lymphocytes
Alaa S. Awad et al.
KIDNEY INTERNATIONAL (2011)
S1P Is Associated with Protection in Human and Experimental Cerebral Malaria
Constance A. M. Finney et al.
MOLECULAR MEDICINE (2011)
A Sphingosine Kinase Form 2 Knockout Sensitizes Mouse Myocardium to Ischemia/Reoxygenation Injury and Diminishes Responsiveness to Ischemic Preconditioning
Donald A. Vessey et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2011)
Therapeutic Effects of Novel Sphingosine-1-Phosphate Receptor Agonist W-061 in Murine DSS Colitis
Yasuaki Sanada et al.
PLOS ONE (2011)
FTY720 (fingolimod) efficacy in an animal model of multiple sclerosis requires astrocyte sphingosine 1-phosphate receptor 1 (S1P1) modulation
Ji Woong Choi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Translational aspects of sphingosine 1-phosphate biology
Susan Pyne et al.
TRENDS IN MOLECULAR MEDICINE (2011)
Discovery of CS-0777: A Potent, Selective, and Orally Active S1P1 Agonist
Takahide Nishi et al.
ACS MEDICINAL CHEMISTRY LETTERS (2011)
S1P4 Receptor Mediates S1P-Induced Vasoconstriction in Normotensive and Hypertensive Rat Lungs
Hiroki Ota et al.
Pulmonary Circulation (2011)
The outs and the ins of sphingosine-1-phosphate in immunity
Sarah Spiegel et al.
NATURE REVIEWS IMMUNOLOGY (2011)
High Expression of Sphingosine 1-Phosphate Receptors, S1P1 and S1P3, Sphingosine Kinase 1, and Extracellular Signal-Regulated Kinase-1/2 Is Associated with Development of Tamoxifen Resistance in Estrogen Receptor-Positive Breast Cancer Patients
Carol Watson et al.
AMERICAN JOURNAL OF PATHOLOGY (2010)
Differential Effects of Sphingosine 1-Phosphate Receptors on Airway and Vascular Barrier Function in the Murine Lung
Saad Sammani et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2010)
Essential Requirement for PP2A Inhibition by the Oncogenic Receptor c-KIT Suggests PP2A Reactivation as a Strategy to Treat c-KIT+ Cancers
Kathryn G. Roberts et al.
CANCER RESEARCH (2010)
Suppression of colitis-driven colon cancer in mice by a novel small molecule inhibitor of sphingosine kinase
Alexander A. Chumanevich et al.
CARCINOGENESIS (2010)
Design and Synthesis of Selective and Potent Orally Active S1P5 Agonists
Henri Mattes et al.
CHEMMEDCHEM (2010)
Antiestrogenic Effects of the Novel Sphingosine Kinase-2 Inhibitor ABC294640
James W. Antoon et al.
ENDOCRINOLOGY (2010)
Sphingosine 1-Phosphate Receptor 4 Uses HER2 (ERBB2) to Regulate Extracellular Signal Regulated Kinase-1/2 in MDA-MB-453 Breast Cancer Cells
Jaclyn S. Long et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Chemorepulsion by blood S1P regulates osteoclast precursor mobilization and bone remodeling in vivo
Masaru Ishii et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2010)
Genetic Sphingosine Kinase 1 Deficiency Significantly Decreases Synovial Inflammation and Joint Erosions in Murine TNF-α-Induced Arthritis
DeAnna A. Baker et al.
JOURNAL OF IMMUNOLOGY (2010)
Inhibition of Sphingosine 1-Phosphate Lyase for the Treatment of Rheumatoid Arthritis: Discovery of (E)-1-(4((1R,2S,3R)-1,2,3,4-Tetrahydroxybutyl)-1H-imidazol-2-yl)ethanone Oxime (LX2931) and (1R,2S,3R)-1-(2-(Isoxazol-3-yl)-1H-imidazol-4-yl)butane-1,2,3,4-tetraol (LX2932)
Jeffrey T. Bagdanoff et al.
JOURNAL OF MEDICINAL CHEMISTRY (2010)
2-Imino-thiazolidin-4-one Derivatives as Potent, Orally Active S1P1 Receptor Agonists
Martin H. Bolli et al.
JOURNAL OF MEDICINAL CHEMISTRY (2010)
Pharmacology and Antitumor Activity of ABC294640, a Selective Inhibitor of Sphingosine Kinase-2
Kevin J. French et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2010)
Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2
Sergio E. Alvarez et al.
NATURE (2010)
An update on sphingosine-1-phosphate and other sphingolipid mediators
Henrik Fyrst et al.
NATURE CHEMICAL BIOLOGY (2010)
STAT3-induced S1PR1 expression is crucial for persistent STAT3 activation in tumors
Heehyoung Lee et al.
NATURE MEDICINE (2010)
Fingolimod (FTY720): discovery and development of an oral drug to treat multiple sclerosis
Volker Brinkmann et al.
NATURE REVIEWS DRUG DISCOVERY (2010)
Structure and Function of Sphingosine-1-Phosphate Lyase, a Key Enzyme of Sphingolipid Metabolism
Florence Bourquin et al.
STRUCTURE (2010)
Targeting the correct HDAC(s) to treat cognitive disorders
Andre Fischer et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2010)
Attenuation of arthritis in rodents by a novel orally-available inhibitor of sphingosine kinase
Leo R. Fitzpatrick et al.
INFLAMMOPHARMACOLOGY (2010)
Efficacy of a novel sphingosine kinase inhibitor in experimental Crohn’s disease
Lynn W. Maines et al.
INFLAMMOPHARMACOLOGY (2010)
Sphingosine 1-phosphate and cancer
Nigel J. Pyne et al.
NATURE REVIEWS CANCER (2010)
Export and functions of sphingosine-1-phosphate
Roger H. Kim et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2009)
Targeting Sphingosine Kinase 1 Inhibits Akt Signaling, Induces Apoptosis, and Suppresses Growth of Human Glioblastoma Cells and Xenografts
Dmitri Kapitonov et al.
CANCER RESEARCH (2009)
Role for sphingosine kinase 1 in colon carcinogenesis
Toshihiko Kawamori et al.
FASEB JOURNAL (2009)
T-bet-dependent S1P5 expression in NK cells promotes egress from lymph nodes and bone marrow
Craig N. Jenne et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2009)
AUY954, a selective S1P1 modulator, prevents experimental autoimmune neuritis
Zhi-Yuan Zhang et al.
JOURNAL OF NEUROIMMUNOLOGY (2009)
Sphingosine-1-phosphate mobilizes osteoclast precursors and regulates bone homeostasis
Masaru Ishii et al.
NATURE (2009)
The many roles of histone deacetylases in development and physiology: implications for disease and therapy
Michael Haberland et al.
NATURE REVIEWS GENETICS (2009)
A critical role for the sphingosine analog AAL-R in dampening the cytokine response during influenza virus infection
David Marsolais et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
The Sphingolipid Transporter Spns2 Functions in Migration of Zebrafish Myocardial Precursors
Atsuo Kawahara et al.
SCIENCE (2009)
Regulation of Histone Acetylation in the Nucleus by Sphingosine-1-Phosphate
Nitai C. Hait et al.
SCIENCE (2009)
STATs in cancer inflammation and immunity: a leading role for STAT3
Hua Yu et al.
NATURE REVIEWS CANCER (2009)
A selective sphingosine kinase 1 inhibitor integrates multiple molecular therapeutic targets in human leukemia
Steven W. Paugh et al.
BLOOD (2008)
Increased survival and reduced renal injury in MRL/Ipr mice treated with a novel sphingosine-1-phosphate receptor agonist
Scott E. Wenderfer et al.
KIDNEY INTERNATIONAL (2008)
Full Pharmacological Efficacy of a Novel S1P1 Agonist That Does Not Require S1P-Like Headgroup Interactions
Pedro J. Gonzalez-Cabrera et al.
MOLECULAR PHARMACOLOGY (2008)
Dendritic cell PAR1-S1P3 signalling couples coagulation and inflammation
Frank Niessen et al.
NATURE (2008)
Therapeutic application of histone deacetylase inhibitors for central nervous system disorders
Aleksey G. Kazantsev et al.
NATURE REVIEWS DRUG DISCOVERY (2008)
Principles of bioactive lipid signalling: lessons from sphingolipids
Yusuf A. Hannun et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)
Constitutively activated STAT3 promotes cell proliferation and survival in the activated B-cell subtype of diffuse large B-cell lymphomas
B. Belinda Ding et al.
BLOOD (2008)
Microarray analysis of altered sphingolipid metabolism reveals prognostic significance of sphingosine kinase 1 in breast cancer
Eugen Ruckhaeberle et al.
BREAST CANCER RESEARCH AND TREATMENT (2008)
A novel sphingosine 1-phosphate receptor agonist, 2-amino-2-propanediol hydrochloride (KRP-203), regulates chronic colitis in interleukin-10 gene-deficient mice
Jinghai Song et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2008)
FTY720 demonstrates promising preclinical activity for chronic lymphocytic leukemia and lymphoblastic leukemia/lymphoma
Qing Liu et al.
BLOOD (2008)
Cutting edge: Modulation of intestinal autoimmunity and IL-2 signaling by sphingosine kinase 2 independent of sphingosine 1-phosphate
Eileen T. Samy et al.
JOURNAL OF IMMUNOLOGY (2007)
FTY720, a new alternative for treating blast crisis chronic myelogenous leukemia and Philadelphia chromosome-positive acute lymphocytic leukemia
Paolo Neviani et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Synthesis and biological evaluation of γ-aminophosphonates as potent, subtype-selective sphingosine 1-phosphate receptor agonists and antagonists
Frank W. Foss et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2007)
Crosstalk between cancer and immune cells: role of STAT3 in the tumour microenvironment
Hua Yu et al.
NATURE REVIEWS IMMUNOLOGY (2007)
Enhancement of capillary leakage and restoration of lymphocyte egress by a chiral S1P1 antagonist in vivo
M. Germana Sanna et al.
NATURE CHEMICAL BIOLOGY (2006)
Entry of muscle satellite cells into the cell cycle requires sphingolipid signaling
Yosuke Nagata et al.
JOURNAL OF CELL BIOLOGY (2006)
S1P1-selective agonist, SEW2871, ameliorates ischemic acute renal failure
YHH Lien et al.
KIDNEY INTERNATIONAL (2006)
Estrogen transactivates EGFR via the sphingosine 1-phosphate receptor Edg-3: the role of sphingosine kinase-1
O Sukocheva et al.
JOURNAL OF CELL BIOLOGY (2006)
Validation of an anti-sphingosine-1-phosphate antibody as a potential therapeutic in reducing growth, invasion, and angiogenesis in multiple tumor lineages
B Visentin et al.
CANCER CELL (2006)
Efficacy of mycophenolic acid combined with KRP-203, a novel immunomodulator, in a rat heart transplantation model
C Suzuki et al.
JOURNAL OF HEART AND LUNG TRANSPLANTATION (2006)
Essential role for sphingosine kinases in neural and vascular development
K Mizugishi et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
Lymphocyte sequestration through S1P lyase inhibition and disruption of S1P gradients
SR Schwab et al.
SCIENCE (2005)
S1P1-selective in vivo-active agonists from high-throughput screening:: Off-the-shelf chemical probes of receptor interactions, signaling, and fate
EJ Jo et al.
CHEMISTRY & BIOLOGY (2005)
Sphingosine 1-phosphate analogs as receptor antagonists
MD Davis et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
KRP-203, a novel synthetic immunosuppressant, prolongs graft survival and attenuates chronic rejection in rat skin and heart allografts
H Shimizu et al.
CIRCULATION (2005)
Synthesis of benzimidazole based analogues of sphingosine-1-phosphate:: discovery of potent, subtype-selective S1P4 receptor agonists
JJ Clemens et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2004)
A novel immunosuppressive agent FTY720 induced Akt dephosphorylation in leukemia cells
Y Matsuoka et al.
BRITISH JOURNAL OF PHARMACOLOGY (2003)
Antiproliferative property of sphingosine 1-phosphate in rat hepatocytes involves activation of Rho via Edg-5
H Ikeda et al.
GASTROENTEROLOGY (2003)
The immune modulator FTY720 targets sphingosine 1-phosphate receptors
V Brinkmann et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists
S Mandala et al.
SCIENCE (2002)
Edg-1, the G protein-coupled receptor for sphingosine-1-phosphate, is essential for vascular maturation
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JOURNAL OF CLINICAL INVESTIGATION (2000)
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