期刊
NATURE REVIEWS DRUG DISCOVERY
卷 7, 期 1, 页码 21-39出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/nrd2399
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资金
- NATIONAL HEART, LUNG, AND BLOOD INSTITUTE [R37HL032854, U54HL070819] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [T32GM007753] Funding Source: NIH RePORTER
- NHLBI NIH HHS [U54HL070819, R37HL032854] Funding Source: Medline
- NIGMS NIH HHS [T32GM07753, T32 GM007753] Funding Source: Medline
Once a rarely used subset of medical treatments, protein therapeutics have increased dramatically in number and frequency of use since the introduction of the first recombinant protein therapeutic-human insulin-25 years ago. Protein therapeutics already have a significant role in almost every field of medicine, but this role is still only in its infancy. This article overviews some of the key characteristics of protein therapeutics, summarizes the more than 130 protein therapeutics used currently and suggests a new classification of these proteins according to their pharmacological action.
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