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J. Schmidt et al.
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Consensus recommendations for the uniform reporting of clinical trials: report of the International Myeloma Workshop Consensus Panel 1
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Qizhen Shi et al.
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Incidence of hematologic malignancies in Europe by morphologic subtype: results of the HAEMACARE project
Milena Sant et al.
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R. Baz et al.
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A Glasmacher et al.
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A phase 2 study of two doses of bortezomib in relapsed or refractory myeloma
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