期刊
NATURE REVIEWS CLINICAL ONCOLOGY
卷 10, 期 1, 页码 52-60出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/nrclinonc.2012.203
关键词
-
类别
Radiotherapy has been driven by constant technological advances since the discovery of X-rays in 1895. Radiotherapy aims to sculpt the optimal isodose on the tumour volume while sparing normal tissues. The benefits are threefold: patient cure, organ preservation and cost-efficiency. The efficacy and tolerance of radiotherapy were demonstrated by randomized trials in many different types of cancer (including breast, prostate and rectum) with a high level of scientific evidence. Such achievements, of major importance for the quality of life of patients, have been fostered during the past decade by linear accelerators with computer-assisted technology. More recently, these developments were augmented by proton and particle beam radiotherapy, usually combined with surgery and medical treatment in a multidisciplinary and personalized strategy against cancer. This article reviews the timeline of 100 years of radiotherapy with a focus on breakthroughs in the physics of radiotherapy and technology during the past two decades, and the associated clinical benefits. Thariat, J. et al. Nat. Rev. Clin. Oncol. 10, 52-60 (2013); published online 27 November 2012; doi:10.1038/nrclinonc.2012.203
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据