期刊
NATURE REVIEWS CLINICAL ONCOLOGY
卷 8, 期 1, 页码 48-55出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/nrclinonc.2010.190
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资金
- Medical Research Council
- Pelican Cancer Foundation
- Prostate UK
- Prostate Cancer Research Centre
- Prostate Cancer Research Foundation
- St Peters Trust
- MRC [G0701302, G1002509] Funding Source: UKRI
- Medical Research Council [G1002509, G0701302] Funding Source: researchfish
In recent years, there has been a growing interest in focal treatment for prostate cancer. Although widely used for the treatment of tumors of the breast and kidney, focal treatment for prostate cancer remains a controversial area. Criticism of focal prostate therapy has been based on the fact that prostate cancer is a multifocal disease. Until now, little attention has been paid to distinguishing between men with unifocal and those with multifocal disease because such information has little clinical relevance when treatment is aimed at the whole gland irrespective of the volume or number of cancers in the prostate. In this Review, we summarize existing knowledge and examine the issue of prostate cancer focality in the context of focal treatment.
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