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Leisure-Time Screen-Based Sedentary Behavior and Leukocyte Telomere Length: Implications for a New Leisure-Time Screen-Based Sedentary Behavior Mechanism
Paul D. Loprinzi
MAYO CLINIC PROCEEDINGS (2015)
The metabolic regulation of aging
Toren Finkel
NATURE MEDICINE (2015)
Cellular senescence in aging and age-related disease: from mechanisms to therapy
Bennett G. Childs et al.
NATURE MEDICINE (2015)
Epigenetic regulation of ageing: linking environmental inputs to genomic stability
Berenice A. Benayoun et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2015)
Exercise Attenuates the Major Hallmarks of Aging
Nuria Garatachea et al.
REJUVENATION RESEARCH (2015)
Human telomere biology: A contributory and interactive factor in aging, disease risks, and protection
Elizabeth H. Blackburn et al.
SCIENCE (2015)
Time-restricted feeding attenuates age-related cardiac decline in Drosophila
Shubhroz Gill et al.
SCIENCE (2015)
Emerging Role of Sirtuin 2 in the Regulation of Mammalian Metabolism
Pedro Gomes et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2015)
Genome-Wide Scan Informed by Age-Related Disease Identifies Loci for Exceptional Human Longevity
Kristen Fortney et al.
PLOS GENETICS (2015)
Inflammation, But Not Telomere Length, Predicts Successful Ageing at Extreme Old Age: A Longitudinal Study of Semi-supercentenarians
Yasumichi Arai et al.
EBIOMEDICINE (2015)
How Cardiomyocytes Make the Heart Old
Zoltan Papp et al.
CURRENT PHARMACEUTICAL BIOTECHNOLOGY (2015)
GWAS of Longevity in CHARGE Consortium Confirms APOE and FOXO3 Candidacy
Linda Broer et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2015)
Intermittent Fasting Results in Tissue-Specific Changes in Bioenergetics and Redox State
Bruno Chausse et al.
PLOS ONE (2015)
Simulated Microgravity Exerts an Age-Dependent Effect on the Differentiation of Cardiovascular Progenitors Isolated from the Human Heart
Tania I. Fuentes et al.
PLOS ONE (2015)
Aging Effects on Cardiac Progenitor Cell Physiology
Marcello Rota et al.
COMPREHENSIVE PHYSIOLOGY (2015)
Stimulating endogenous cardiac repair
Amanda Finan et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2015)
Nucleostemin Rejuvenates Cardiac Progenitor Cells and Antagonizes Myocardial Aging
Nirmala Hariharan et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2015)
Progerin expression disrupts critical adult stem cell functions involved in tissue repair
Laurin Marie Pacheco et al.
AGING-US (2014)
Histone methylation and aging: Lessons learned from model systems
Brenna S. McCauley et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS (2014)
A Proliferative Burst during Preadolescence Establishes the Final Cardiomyocyte Number
Nawazish Naqvi et al.
CELL (2014)
Geroscience: Linking Aging to Chronic Disease
Brian K. Kennedy et al.
CELL (2014)
CENP-A is essential for cardiac progenitor cell proliferation
Michael McGregor et al.
CELL CYCLE (2014)
A SIRT7-Dependent Acetylation Switch of GABPβ1 Controls Mitochondrial Function
Dongryeol Ryu et al.
CELL METABOLISM (2014)
Adult c-kitpos Cardiac Stem Cells Fulfill Koch's Postulates as Causal Agents for Cardiac Regeneration
Daniele Torella et al.
CIRCULATION RESEARCH (2014)
Metabolic Dysfunction Consistent With Premature Aging Results From Deletion of Pim Kinases
Shabana Din et al.
CIRCULATION RESEARCH (2014)
An Essential Role for Senescent Cells in Optimal Wound Healing through Secretion of PDGF-AA
Marco Demaria et al.
DEVELOPMENTAL CELL (2014)
PRAS40 prevents development of diabetic cardiomyopathy and improves hepatic insulin sensitivity in obesity
Mirko Voelkers et al.
EMBO MOLECULAR MEDICINE (2014)
Genome wide DNA methylation profiling for epigenetic alteration in coronary artery disease patients
Priyanka Sharma et al.
GENE (2014)
Histone variants: dynamic punctuation in transcription
Christopher M. Weber et al.
GENES & DEVELOPMENT (2014)
Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age
Joris Deelen et al.
HUMAN MOLECULAR GENETICS (2014)
Effects of 5 days of head-down bed rest, with and without short-arm centrifugation as countermeasure, on cardiac function in males (BR-AG1 study)
E. G. Caiani et al.
JOURNAL OF APPLIED PHYSIOLOGY (2014)
Aging and epigenetic drift: a vicious cycle
Jean-Pierre Issa
JOURNAL OF CLINICAL INVESTIGATION (2014)
Chronic Inflammation (Inflammaging) and Its Potential Contribution to Age-Associated Diseases
Claudio Franceschi et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2014)
Mesenchymal-endothelial transition contributes to cardiac neovascularization
Eric Ubil et al.
NATURE (2014)
Prepare for human testing
Luigi Fontana et al.
NATURE (2014)
AgeFactDB-the JenAge Ageing Factor Database-towards data integration in ageing research
Rolf Huehne et al.
NUCLEIC ACIDS RESEARCH (2014)
Complex I Deficiency Due to Selective Loss of Ndufs4 in the Mouse Heart Results in Severe Hypertrophic Cardiomyopathy
Edward T. Chouchani et al.
PLOS ONE (2014)
Existing cardiomyocytes generate cardiomyocytes at a low rate after birth in mice
Shah R. Ali et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Comparative interactomes of SIRT6 and SIRT7: Implication of functional links to aging
Namgyu Lee et al.
PROTEOMICS (2014)
mTOR inhibition improves immune function in the elderly
Joan B. Mannick et al.
SCIENCE TRANSLATIONAL MEDICINE (2014)
The cardiac stem cell compartment is indispensable for myocardial cell homeostasis, repair and regeneration in the adult
Bernardo Nadal-Ginard et al.
STEM CELL RESEARCH (2014)
Histone H3.3 and its proteolytically processed form drive a cellular senescence programme
Luis F. Duarte et al.
NATURE COMMUNICATIONS (2014)
Leucocyte telomere length and risk of cardiovascular disease: systematic review and meta-analysis
Philip C. Haycock et al.
BMJ-BRITISH MEDICAL JOURNAL (2014)
The SIRT1 Activator SRT1720 Extends Lifespan and Improves Health of Mice Fed a Standard Diet
Sarah J. Mitchell et al.
CELL REPORTS (2014)
Stress and Cardiovascular Disease: An Update on Current Knowledge
Andrew Steptoe et al.
ANNUAL REVIEW OF PUBLIC HEALTH, VOL 34 (2013)
Diabetes mellitus activates fetal gene program and intensifies cardiac remodeling and oxidative stress in aged spontaneously hypertensive rats
Camila Moreno Rosa et al.
CARDIOVASCULAR DIABETOLOGY (2013)
Adult c-kitpos Cardiac Stem Cells Are Necessary and Sufficient for Functional Cardiac Regeneration and Repair
Georgina M. Ellison et al.
CELL (2013)
Growth Differentiation Factor 11 Is a Circulating Factor that Reverses Age-Related Cardiac Hypertrophy
Francesco S. Loffredo et al.
CELL (2013)
Mechanistic Target of Rapamycin Complex 2 Protects the Heart From Ischemic Damage
Mirko Voelkers et al.
CIRCULATION (2013)
Rejuvenation of Human Cardiac Progenitor Cells With Pim-1 Kinase
Sadia Mohsin et al.
CIRCULATION RESEARCH (2013)
Aberrant DNA methylation profiles in the premature aging disorders Hutchinson-Gilford Progeria and Werner Syndrome
Holger Heyn et al.
EPIGENETICS (2013)
Premature Impairment of Methylation Pathway and Cardiac Metabolic Dysfunction in fa/fa Obese Zucker Rats
Nuria M. de Castro et al.
JOURNAL OF PROTEOME RESEARCH (2013)
Mammalian heart renewal by pre-existing cardiomyocytes
Samuel E. Senyo et al.
NATURE (2013)
Role of telomere dysfunction in cardiac failure in Duchenne muscular dystrophy
Foteini Mourkioti et al.
NATURE CELL BIOLOGY (2013)
Senescent cells harbour features of the cancer epigenome
Hazel A. Cruickshanks et al.
NATURE CELL BIOLOGY (2013)
Identification of seven loci affecting mean telomere length and their association with disease
Veryan Codd et al.
NATURE GENETICS (2013)
Cardiac Aging and Rejuvenation A Sense of Humors?
Thomas A. Rando et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
Severity of cardiomyopathy associated with adenine nucleotide translocator-1 deficiency correlates with mtDNA haplogroup
Kevin A. Strauss et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Social stress up-regulates inflammatory gene expression in the leukocyte transcriptome via β-adrenergic induction of myelopoiesis
Nicole D. Powell et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Cardiomyocyte proliferation contributes to heart growth in young humans
Mariya Mollova et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
A Natural Product Telomerase Activator as Part of a Health Maintenance Program: Metabolic and Cardiovascular Response
Calvin B. Harley et al.
REJUVENATION RESEARCH (2013)
Reducing indoor air pollution by air conditioning is associated with improvements in cardiovascular health among the general population
Lian-Yu Lin et al.
SCIENCE OF THE TOTAL ENVIRONMENT (2013)
Metformin improves healthspan and lifespan in mice
Alejandro Martin-Montalvo et al.
NATURE COMMUNICATIONS (2013)
Do Telomeres Adapt to Physiological Stress? Exploring the Effect of Exercise on Telomere Length and Telomere-Related Proteins
Andrew T. Ludlow et al.
BIOMED RESEARCH INTERNATIONAL (2013)
Porcine Models of Accelerated Coronary Atherosclerosis: Role of Diabetes Mellitus and Hypercholesterolemia
Damir Hamamdzic et al.
JOURNAL OF DIABETES RESEARCH (2013)
Do we age faster in absence of gravity?
Camillo Di Giulio
FRONTIERS IN PHYSIOLOGY (2013)
Cardiac Hegemony of Senescence
Sailay Siddiqi et al.
CURRENT GERIATRICS REPORTS (2013)
Heterochronic parabiosis for the study of the effects of aging on stem cells and their niches
Irina M. Conboy et al.
CELL CYCLE (2012)
Administration of Cardiac Stem Cells in Patients With Ischemic Cardiomyopathy: The SCIPIO Trial Surgical Aspects and Interim Analysis of Myocardial Function and Viability by Magnetic Resonance
Atul R. Chugh et al.
CIRCULATION (2012)
DelK32-lamin A/C has abnormal location and induces incomplete tissue maturation and severe metabolic defects leading to premature death
Anne T. Bertrand et al.
HUMAN MOLECULAR GENETICS (2012)
Human Cardiac Progenitor Cells Engineered With Pim-I Kinase Enhance Myocardial Repair
Sadia Mohsin et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2012)
Chronic Exercise Modifies Age-Related Telomere Dynamics in a Tissue-Specific Fashion
Andrew T. Ludlow et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2012)
Job strain as a risk factor for coronary heart disease: a collaborative meta-analysis of individual participant data
Mika Kivimaeki et al.
LANCET (2012)
The sirtuin SIRT6 blocks IGF-Akt signaling and development of cardiac hypertrophy by targeting c-Jun
Nagalingam R. Sundaresan et al.
NATURE MEDICINE (2012)
Stress and cardiovascular disease
Andrew Steptoe et al.
NATURE REVIEWS CARDIOLOGY (2012)
mTOR signalling: the molecular interface connecting metabolic stress, aging and cardiovascular diseases
Z. Yang et al.
OBESITY REVIEWS (2012)
Rapamycin Reverses Elevated mTORC1 Signaling in Lamin A/C-Deficient Mice, Rescues Cardiac and Skeletal Muscle Function, and Extends Survival
Fresnida J. Ramos et al.
SCIENCE TRANSLATIONAL MEDICINE (2012)
Reduced Life- and Healthspan in Mice Carrying a Mono-Allelic BubR1 MVA Mutation
Tobias Wijshake et al.
PLOS GENETICS (2012)
Historical review, epidemiology and natural history of degenerative mitral valve disease
Michele Borgarelli et al.
JOURNAL OF VETERINARY CARDIOLOGY (2012)
Genetic variation in insulin/IGF-1 signaling pathways and longevity
Elad Ziv et al.
AGEING RESEARCH REVIEWS (2011)
The telomerase activator TA-65 elongates short telomeres and increases health span of adult/old mice without increasing cancer incidence
Bruno Bernardes de Jesus et al.
AGING CELL (2011)
Effects of Age and Heart Failure on Human Cardiac Stem Cell Function
Daniela Cesselli et al.
AMERICAN JOURNAL OF PATHOLOGY (2011)
Cellular Senescence, Vascular Disease, and Aging Part 1 of a 2-Part Review
Jason C. Kovacic et al.
CIRCULATION (2011)
Cellular Senescence, Vascular Disease, and Aging Part 2 of a 2-Part Review: Clinical Vascular Disease in the Elderly
Jason C. Kovacic et al.
CIRCULATION (2011)
Molecular mechanisms of cardiomyocyte aging
Anna Sheydina et al.
CLINICAL SCIENCE (2011)
Cellular senescence: putting the paradoxes in perspective
Judith Campisi
CURRENT OPINION IN GENETICS & DEVELOPMENT (2011)
Characterization of a Transgenic Short Hairpin RNA-Induced Murine Model of Tafazzin Deficiency
Meghan S. Soustek et al.
HUMAN GENE THERAPY (2011)
Cardiac and Skeletal Muscle Defects in a Mouse Model of Human Barth Syndrome
Devrim Acehan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Cardiovascular Changes During Maturation and Ageing in Male and Female Spontaneously Hypertensive Rats
Vincent Chan et al.
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2011)
Obesity Induces Signs of Premature Cardiac Aging in Younger Patients The Role of Mitochondria
Bernd Niemann et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2011)
被撤回的出版物: Cardiac stem cells in patients with ischaemic cardiomyopathy (SCIPIO): initial results of a randomised phase 1 trial (Retracted article. See vol. 393, pg. 1084, 2019)
Roberto Bolli et al.
LANCET (2011)
Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
Darren J. Baker et al.
NATURE (2011)
Nucleolar stress is an early response to myocardial damage involving nucleolar proteins nucleostemin and nucleophosmin
Daniele Avitabile et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Transient Regenerative Potential of the Neonatal Mouse Heart
Enzo R. Porrello et al.
SCIENCE (2011)
Splicing-Directed Therapy in a New Mouse Model of Human Accelerated Aging
Fernando G. Osorio et al.
SCIENCE TRANSLATIONAL MEDICINE (2011)
Post-natal myogenic and adipogenic developmental Defects and metabolic impairment upon loss of A-type lamins
Nard Kubben et al.
NUCLEUS (2011)
CENP-A, a protein required for chromosome segregation in mitosis, declines with age in islet but not exocrine cells
Seung-Hee Lee et al.
AGING-US (2010)
The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression
Jean -Philippe Coppe et al.
ANNUAL REVIEW OF PATHOLOGY-MECHANISMS OF DISEASE (2010)
Short Telomeres and Stem Cell Exhaustion Model Duchenne Muscular Dystrophy in mdx/mTR Mice
Alessandra Sacco et al.
CELL (2010)
Silent Information Regulator 1 Protects the Heart From Ischemia/Reperfusion
Chiao-Po Hsu et al.
CIRCULATION (2010)
Deacetylation of FoxO by Sirt1 Plays an Essential Role in Mediating Starvation-Induced Autophagy in Cardiac Myocytes
Nirmala Hariharan et al.
CIRCULATION RESEARCH (2010)
Roles of Werner syndrome protein in protection of genome integrity
Marie L. Rossi et al.
DNA REPAIR (2010)
The role of inflammatory and fibrogenic pathways in heart failure associated with aging
Wei Chen et al.
HEART FAILURE REVIEWS (2010)
Cardioprotective effect of intermittent fasting is associated with an elevation of adiponectin levels in rats
Ruiqian Wan et al.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2010)
Elevated Histone Expression Promotes Life Span Extension
Jason Feser et al.
MOLECULAR CELL (2010)
Reduced histone biosynthesis and chromatin changes arising from a damage signal at telomeres
Roderick J. O'Sullivan et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2010)
Association of common genetic variation in the insulin/IGF1 signaling pathway with human longevity
Ludmila Pawlikowska et al.
AGING CELL (2009)
Enhancement of Myocardial Regeneration Through Genetic Engineering of Cardiac Progenitor Cells Expressing Pim-1 Kinase
Kimberlee M. Fischer et al.
CIRCULATION (2009)
Physical Exercise Prevents Cellular Senescence in Circulating Leukocytes and in the Vessel Wall
Christian Werner et al.
CIRCULATION (2009)
CENPA a Genomic Marker for Centromere Activity and Human Diseases
Manuel M. Valdivia et al.
CURRENT GENOMICS (2009)
Association between leukocyte telomere shortening and exposure to traffic pollution: a cross-sectional study on traffic officers and indoor office workers
Mirjam Hoxha et al.
ENVIRONMENTAL HEALTH (2009)
An operational definition of epigenetics
Shelley L. Berger et al.
GENES & DEVELOPMENT (2009)
Chronic intermittent fasting improves the survival following large myocardial ischemia by activation of BDNF/VEGF/PI3K signaling pathway
Rajesh G. Katare et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2009)
Histone H4 lysine 16 acetylation regulates cellular lifespan
Weiwei Dang et al.
NATURE (2009)
Evidence for Cardiomyocyte Renewal in Humans
Olaf Bergmann et al.
SCIENCE (2009)
Caloric restriction, SIRT1 and longevity
Caries Canto et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2009)
Sirt7 increases stress resistance of cardiomyocytes and prevents apoptosis and inflammatory cardiomyopathy in mice
Olesya Vakhrusheva et al.
CIRCULATION RESEARCH (2008)
Myocardial induction of nucleostemin in response to postnatal growth and pathological challenge
Sailay Siddiqi et al.
CIRCULATION RESEARCH (2008)
The aging cardiomyocyte: A mini-review
D. Bernhard et al.
GERONTOLOGY (2008)
Adult stem cell maintenance and tissue regeneration in the ageing context: the role for A-type lamins as intrinsic modulators of ageing in adult stem cells and their niches
Vanja Pekovic et al.
JOURNAL OF ANATOMY (2008)
Effects of physical exercise on myocardial telomere-regulating proteins, survival pathways, and apoptosis
Christian Werner et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2008)
Cellular senescence and organismal aging
Jessie C. Jeyapalan et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2008)
Pim-1 regulates cardiomyocyte survival downstream of Akt
John A. Muraski et al.
NATURE MEDICINE (2007)
Sirt1 regulates aging and resistance to oxidative stress in the heart
Ralph R. Alcendor et al.
CIRCULATION RESEARCH (2007)
Aging-associated vascular phenotype in mutant mice with low levels of BubR1
Takuya Matsumoto et al.
STROKE (2007)
Inactivity induces increases in abdominal fat
Matthew J. Laye et al.
JOURNAL OF APPLIED PHYSIOLOGY (2007)
Molecular bases of progeroid syndromes
Claire L. Navarro et al.
HUMAN MOLECULAR GENETICS (2006)
Akt promotes increased cardiomyocyte cycling and expansion of the cardiac progenitor cell population
Natalie Gude et al.
CIRCULATION RESEARCH (2006)
Pathology and nuclear abnormalities in hearts of transgenic mice expressing M371K lamin A encoded by an LMNA mutation causing Emery-Dreifuss muscular dystrophy
Yuexia Wang et al.
HUMAN MOLECULAR GENETICS (2006)
Objective evaluation of changes in left ventricular and atrial volumes during parabolic flight using real-time three-dimensional echocardiography
E. G. Caiani et al.
JOURNAL OF APPLIED PHYSIOLOGY (2006)
Mice deficient in telomerase activity develop hypertension because of an excess of endothelin production
Gema Perez-Rivero et al.
CIRCULATION (2006)
Vascular smooth muscle cells undergo telomere-based senescence in human atherosclerosis - Effects of telomerase and oxidative stress
Charles Matthews et al.
CIRCULATION RESEARCH (2006)
Cardiac regeneration
P Anversa et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2006)
Cardiac myocyte apoptosis is associated with increased DNA damage and decreased survival in murine models of obesity
LA Barouch et al.
CIRCULATION RESEARCH (2006)
Cardioprotection by intermittent fasting in rats
I Ahmet et al.
CIRCULATION (2005)
Expression of an LMNA-N195K variant of A-type lamins results in cardiac conduction defects and death in mice
LC Mounkes et al.
HUMAN MOLECULAR GENETICS (2005)
Myocardial regeneration by activation of multipotent cardiac stem cells in ischemic heart failure
K Urbanek et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Rejuvenation of aged progenitor cells by exposure to a young systemic environment
IM Conboy et al.
NATURE (2005)
A novel VNTR enhancer within the SIRT3 gene, a human homologue of SIR2, is associated with survival at oldest ages
D Bellizzi et al.
GENOMICS (2005)
Targeted expression of cyclin D2 results in cardiomyocyte DNA synthesis and infarct regression in transgenic mice
KBS Pasumarthi et al.
CIRCULATION RESEARCH (2005)
Mouse model carrying H222P-Lmna mutation develops muscular dystrophy and dilated cardiomyopathy similar to human striated muscle laminopathies
T Arimura et al.
HUMAN MOLECULAR GENETICS (2005)
Cardiac stem cell and myocyte aging, heart failure, and insulin-like growth factor-1 overexpression
D Torella et al.
CIRCULATION RESEARCH (2004)
Expression of telomerase RNA template, but not telomerase reverse transcriptase, is limiting for telomere length maintenance in vivo
YJ Chiang et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Essential role of limiting telomeres in the pathogenesis of Werner syndrome
S Chang et al.
NATURE GENETICS (2004)
Premature ageing in mice expressing defective mitochondrial DNA polymerase
A Trifunovic et al.
NATURE (2004)
Senescence and death of primitive cells and myocytes lead to premature cardiac aging and heart failure
C Chimenti et al.
CIRCULATION RESEARCH (2003)
Adult cardiac stem cells are multipotent and support myocardial regeneration
AP Beltrami et al.
CELL (2003)
WRN, the protein deficient in Werner syndrome, plays a critical structural role in optimizing DNA repair
LS Chen et al.
AGING CELL (2003)
Cardiac lipid accumulation associated with diastolic dysfunction in obese mice
C Christoffersen et al.
ENDOCRINOLOGY (2003)
Telomerase is required to slow telomere shortening and extend replicative lifespan of HSCs during serial transplantation
RC Allsopp et al.
BLOOD (2003)
Mouse models for telomere and telomerase biology
C Cheong et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2003)
A progeroid syndrome in mice is caused by defects in A-type lamins
LC Mounkes et al.
NATURE (2003)
Cardiomyocyte death and the ageing and failing heart
DF Goldspink et al.
EXPERIMENTAL PHYSIOLOGY (2003)
Age-dependent changes in metabolism, contractile function, and ischemic sensitivity in hearts from db/db mice
E Aasum et al.
DIABETES (2003)
Ablation of telomerase and telomere loss leads to cardiac dilatation and heart failure associated with p53 upregulation
A Leri et al.
EMBO JOURNAL (2003)
Defective prelamin A processing and muscular and adipocyte alterations in Zmpste24 metalloproteinase-deficient mice
AM Pendás et al.
NATURE GENETICS (2002)
bcl-2 overexpression promotes myocyte proliferation
F Limana et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Endothelial cell senescence in human atherosclerosis - Role of telomere in endothelial dysfunction
T Minamino et al.
CIRCULATION (2002)
Myocyte growth and cardiac repair
P Anversa et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2002)
Many ways to telomere dysfunction:: in vivo studies using mouse models
FA Goytisolo et al.
ONCOGENE (2002)
Telomerase reverse transcriptase promotes cardiac muscle cell proliferation, hypertrophy, and survival
H Oh et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Diabetes-induced accelerated atherosclerosis in swine
RG Gerrity et al.
DIABETES (2001)
Telomere shortening is an in vivo marker of myocyte replication and aging
J Kajstura et al.
AMERICAN JOURNAL OF PATHOLOGY (2000)