期刊
NATURE PROTOCOLS
卷 6, 期 9, 页码 1429-1442出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/nprot.2011.372
关键词
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资金
- National Research Foundation of Korea
- Korean government [20100017649]
- Pohang Iron and Steel Company (POSCO)
- National Science Foundation, National Institutes of Health, Welch [F1515]
- Packard Foundations
- Carnegie Institution for Science
- National Science Foundation
- Division Of Integrative Organismal Systems
- Direct For Biological Sciences [1026003] Funding Source: National Science Foundation
AraNet is a functional gene network for the reference plant Arabidopsis and has been constructed in order to identify new genes associated with plant traits. It is highly predictive for diverse biological pathways and can be used to prioritize genes for functional screens. Moreover, AraNet provides a web-based tool with which plant biologists can efficiently discover novel functions of Arabidopsis genes ( http://www.functionalnet.org/aranet/). This protocol explains how to conduct network-based prediction of gene functions using AraNet and how to interpret the prediction results. Functional discovery in plant biology is facilitated by combining candidate prioritization by AraNet with focused experimental tests.
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