期刊
NATURE NEUROSCIENCE
卷 21, 期 9, 页码 1144-1146出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/s41593-018-0217-y
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资金
- MRC [MR/N026063/1] Funding Source: UKRI
- Medical Research Council [MR/N026063/1] Funding Source: Medline
A study has found that young male mice with a mutation of the autism-associated gene Chd8 show abnormal behaviors and elevated neuronal activation in several brain areas under stressful conditions, while female mice with the same mutation have reduced baseline neuronal activity, which may protect them from developing these abnormal phenotypes.
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