期刊
NATURE NEUROSCIENCE
卷 17, 期 5, 页码 667-+出版社
NATURE PORTFOLIO
DOI: 10.1038/nn.3695
关键词
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资金
- Austrian Academy of Sciences
- University of Zurich
- Swiss Federal Institute of Technology, Roche
- Swiss National Science Foundation
- National Center of Competence in Research Neural Plasticity and Repair
- Gonville and Caius College fellowship
- Cancer Research UK [11832] Funding Source: researchfish
Small non-coding RNAs (sncRNAs) are potential vectors at the interface between genes and environment. We found that traumatic stress in early life altered mouse microRNA (miRNA) expression, and behavioral and metabolic responses in the progeny. Injection of sperm RNAs from traumatized males into fertilized wild-type oocytes reproduced the behavioral and metabolic alterations in the resulting offspring.
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