期刊
NATURE NEUROSCIENCE
卷 18, 期 2, 页码 188-190出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/nn.3900
关键词
-
资金
- Minerva Foundation
- Israel Science Foundation [26613, 281171]
Broad generalization of negative memories is a potential etiology for anxiety disorders, yet the underlying mechanisms remain unknown. We developed a non-human primate model that replicates behavioral observations in humans and identifies specific changes in tuning properties of amygdala neurons: the width of auditory tuning increases with the distance of its center from the conditioned stimulus. This center-width relationship can account for better detection and at the same time explain the wide stimulus generalization.
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