期刊
NATURE NEUROSCIENCE
卷 16, 期 10, 页码 1492-+出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/nn.3515
关键词
-
资金
- Wellcome Trust [WT088312AIA, 098362/Z/12/Z, 091593/Z/10/Z]
- Medical Research Council [G1000411]
Prior experience is critical for decision-making. It enables explicit representation of potential outcomes and provides training to valuation mechanisms. However, we can also make choices in the absence of prior experience by merely imagining the consequences of a new experience. Using functional magnetic resonance imaging repetition suppression in humans, we examined how neuronal representations of novel rewards can be constructed and evaluated. A likely novel experience was constructed by invoking multiple independent memories in hippocampus and medial prefrontal cortex. This construction persisted for only a short time period, during which new associations were observed between the memories for component items. Together, these findings suggest that, in the absence of direct experience, coactivation of multiple relevant memories can provide a training signal to the valuation system that allows the consequences of new experiences to be imagined and acted on.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据