4.7 Article

Lag normalization in an electrically coupled neural network

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NATURE NEUROSCIENCE
卷 16, 期 2, 页码 154-156

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NATURE PUBLISHING GROUP
DOI: 10.1038/nn.3308

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资金

  1. US National Science Foundation [PHY-1058202, EF-0928048]
  2. National Science Foundation [PHY-1066293]
  3. Canadian Institutes of Health Research [342202-2007]
  4. Foundation for Fighting Blindness (Canada)
  5. Division Of Physics
  6. Direct For Mathematical & Physical Scien [1058202] Funding Source: National Science Foundation
  7. Emerging Frontiers
  8. Direct For Biological Sciences [0928048] Funding Source: National Science Foundation

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Moving objects can cover large distances while they are processed by the eye, usually resulting in a spatially lagged retinal response. We identified a network of electrically coupled motion-coding neurons in mouse retina that act collectively to register the leading edges of moving objects at a nearly constant spatial location, regardless of their velocity. These results reveal a previously unknown neurophysiological substrate for lag normalization in the visual system.

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