期刊
NATURE NEUROSCIENCE
卷 16, 期 12, 页码 1731-1733出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/nn.3573
关键词
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资金
- US National Institutes of Health [MH093887-01]
- EMBL
- German Research Foundation (DFG) [GR 3619/2-1, 3619/3-1, GR 3619/4-11]
- Chica and Heinz Schaller Research Foundation
The neural circuits mediating fear to naturalistic threats are poorly understood. We found that functionally independent populations of neurons in the ventromedial hypothalamus (VMH), a region that has been implicated in feeding, sex and aggression, are essential for predator and social fear in mice. Our results establish a critical role for VMH in fear and have implications for selective intervention in pathological fear in humans.
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