期刊
NATURE NEUROSCIENCE
卷 15, 期 10, 页码 1371-1373出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/nn.3218
关键词
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资金
- Research Council of Norway [191699]
- PEW Charitable Trust [2009-000068001]
- US National Institutes of Health [1DPIOD008324]
In honeybee societies, distinct caste phenotypes are created from the same genotype, suggesting a role for epigenetics in deriving these behaviorally different phenotypes. We found no differences in DNA methylation between irreversible worker and queen castes, but substantial differences between nurses and forager subcastes. Reverting foragers back to nurses reestablished methylation levels for a majority of genes and provides, to the best of our knowledge, the first evidence in any organism of reversible epigenetic changes associated with behavior.
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