期刊
NATURE NEUROSCIENCE
卷 14, 期 11, 页码 1390-1397出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/nn.2947
关键词
-
资金
- Interuniversity Attraction Poles
- FNRS (Fonds de la Recherche Scientifique)
- ARC (Actions de Recherche Concertees-Communaute francaise de Belgique)
- Flemish Government, the Fund for Scientific Research-Flemish Government [G.0677.09, G.0676.09]
- Belgian Science Policy [IUAP-P6/30]
- Association Francaise contre les Myopathies (AFM)
- Geneeskundige stichting Koningin Elisabeth
- Motor Neurone Disease Association [70/130]
Blood vessels in the nervous system have traditionally been considered neutral bystanders that only passively adapt their structure and function in response to the needs of neural cells. Emerging evidence suggests, however, that vessels and angiogenic molecules actively participate in the pathogenesis of neurological disorders. Here we will discuss molecular insights into neurological disorders resulting either from excessive vessel growth (cerebral vascular malformations) or improper vessel regression (neurodegeneration and white matter lesions). These genetic insights offer alternative therapeutic options, some of which are being evaluated in the clinic.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据