期刊
NATURE NEUROSCIENCE
卷 12, 期 1, 页码 85-91出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/nn.2237
关键词
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资金
- Japan Society for the Promotion of Science
- Center of Excellence Program
- Ministry of Education, Culture, Sports, Science and Technology, Japan
Our voluntary behaviors are thought to be controlled by top-down signals from the prefrontal cortex that modulate neural processing in the posterior cortices according to the behavioral goal. However, we have insufficient evidence for the causal effect of the top-down signals. We applied a single-pulse transcranial magnetic stimulation over the human prefrontal cortex and measured the strength of the top-down signals as an increase in the efficiency of neural impulse transmission. The impulse induced by the stimulation transmitted to different posterior visual areas depending on the domain of visual features to which subjects attended. We also found that the amount of impulse transmission was associated with the level of attentional preparation and the performance of visual selective-attention tasks, consistent with the causal role of prefrontal top-down signals.
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