期刊
NATURE NANOTECHNOLOGY
卷 9, 期 5, 页码 397-404出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/NNANO.2014.38
关键词
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资金
- Institute for Basic Science
- Center for Advanced Soft Electronics under the Global Frontier Research Program of the Ministry of Science, ICT and Future Planning, Korea [2013M3A6A5073180]
- Basic Science Research Program of the National Research Foundation of Korea (NRF) - Ministry of Science, ICT and Future Planning [2012R1A1A1004925]
- Cockrell School of Engineering of the University of Texas at Austin
- Global Research Laboratory Program through the NRF [2012040157]
Wearable systems that monitor muscle activity, store data and deliver feedback therapy are the next frontier in personalized medicine and healthcare. However, technical challenges, such as the fabrication of high-performance, energy-efficient sensors and memory modules that are in intimate mechanical contact with soft tissues, in conjunction with controlled delivery of therapeutic agents, limit the wide-scale adoption of such systems. Here, we describe materials, mechanics and designs for multifunctional, wearable-on-the-skin systems that address these challenges via monolithic integration of nanomembranes fabricated with a top-down approach, nanoparticles assembled by bottom-up methods, and stretchable electronics on a tissue-like polymeric substrate. Representative examples of such systems include physiological sensors, non-volatile memory and drug-release actuators. Quantitative analyses of the electronics, mechanics, heat-transfer and drug-diffusion characteristics validate the operation of individual components, thereby enabling system-level multifunctionalities.
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