期刊
NATURE METHODS
卷 9, 期 5, 页码 465-U72出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/NMETH.1973
关键词
-
资金
- Canadian Institute of Health Research Regenerative Medicine and Nanomedicine Team [RMF-82497]
Induced pluripotent stem cells (iPSCs) are typically derived in adherent culture. Here we report fast and efficient derivation of mouse iPSCs in stirred suspension bioreactors, with and without the use of c-Myc. Suspension-reprogrammed cells expressed pluripotency markers, showed multilineage differentiation in vitro and in vivo, and contributed to the germline in chimeric mice. Suspension reprogramming has the potential to accelerate and standardize iPSC research.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据