期刊
NATURE METHODS
卷 8, 期 2, 页码 135-U52出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/NMETH.1556
关键词
-
资金
- US National Institutes of Health [AG034988, EB010244]
- Boehringer Ingelheim Fonds
Identification of genes regulating fat accumulation is important for basic and medical research; genetic screening for those genes in Caenorhabditis elegans, a widely used model organism, requires in vivo quantification of lipids. We demonstrated RNA interference screening based on quantitative imaging of lipids with label-free stimulated Raman scattering (SRS) microscopy, which overcomes major limitations of coherent anti-Stokes Raman scattering microscopy. Our screening yielded eight new genetic regulators of fat storage.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据