4.8 Article

The promise of optogenetics in cell biology: interrogating molecular circuits in space and time

期刊

NATURE METHODS
卷 8, 期 1, 页码 35-38

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NATURE PUBLISHING GROUP
DOI: 10.1038/NMETH.F.326

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资金

  1. Cancer Research Institute
  2. US National Institutes of Health (NIH) [EY016546, AI067699]
  3. National Science Foundation (NSF) [BES-0547637, EEC-0540879, CBET-0943302]
  4. Office of Naval Research [N00014-10-1-0245]
  5. NSF Synthetic Biology Engineering Research Center
  6. NIH [EY016546, GM084040, GM55040, GM62583, GM081879]
  7. Howard Hughes Medical Institute
  8. Packard Foundation
  9. NATIONAL EYE INSTITUTE [PN2EY016546, PN1EY016546] Funding Source: NIH RePORTER
  10. NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES [R01AI067699, R56AI067699] Funding Source: NIH RePORTER
  11. NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [P50GM081879, R01GM062583, R01GM095765, R01GM084040, R01GM055040] Funding Source: NIH RePORTER

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Optogenetic modules offer cell biologists unprecedented new ways to poke and prod cells. The combination of these precision perturbative tools with observational tools, such as fluorescent proteins, may dramatically accelerate our ability to understand the inner workings of the cell.

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