期刊
NATURE METHODS
卷 7, 期 4, 页码 299-301出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/NMETH.1443
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资金
- US National Institutes of Health [HL003676, RR014758, RR003034, NS45012, HG004436]
- American Heart Association [09GRNT2300003]
- Department of Veterans Affairs
- National Institutes of Health [GM074913]
direct observation of haplotypes is still technically challenging. here we report a method for the determination of haplotypes through chromosome microdissection. We determined human long-range chromosomal haplotypes with more than 98.85% accuracy at 24,245 genome-wide heterozygous single-nucleotide polymorphism (SNP) loci.
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