4.8 Article

Programmed subcellular release for studying the dynamics of cell detachment

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NATURE METHODS
卷 6, 期 3, 页码 211-213

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NATURE PUBLISHING GROUP
DOI: 10.1038/NMETH.1299

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  1. US National Institutes of Health
  2. National Science Foundation
  3. Howard Hughes Medical Institution
  4. Achievement Awards for College Scientists foundation
  5. NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING [R21EB008259] Funding Source: NIH RePORTER

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Cell detachment is central to a broad range of physiopathological changes, but there are no quantitative methods to study this process. Here we report programmed subcellular release, a method for spatially and temporally controlled cellular detachment, and present quantitative results of the detachment dynamics of 3T3 fibroblasts at the subcellular level.

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