期刊
NATURE METHODS
卷 5, 期 4, 页码 291-292出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/nmeth0408-291
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资金
- NIGMS NIH HHS [GM33063, GM69968] Funding Source: Medline
- NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM069968, R01GM033063, R37GM033063] Funding Source: NIH RePORTER
Here we introduce a new shorthand nomenclature for designating the disaccharide subunit structure of all glycosaminoglycans as a way to compare compositions and describe linear sequences. Each disaccharide structural code (DSC) comprises four alphanumeric characters that reflect the actual substituents and isomeric characteristics of each component sugar. Larger structures can be represented easily by forming concatamers. The structural transparency of this new nomenclature eliminates the need for ambiguous acronyms or difficult numeric representations.
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