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Waking up HSCs: a new role for E-selectin

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NATURE MEDICINE
卷 18, 期 11, 页码 1613-1614

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NATURE PUBLISHING GROUP
DOI: 10.1038/nm.2992

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Two anatomical niches for hematopoietic stem cells (HSCs) have been reported in the bone marrow, but a distinct function for each of these niches has remained unclear. A new role in stem cell proliferation has now been identified for the adhesion molecule E-selectin expressed by bone marrow endothelial cells at the vascular niche (pages 1651-1657).

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