期刊
NATURE MEDICINE
卷 17, 期 7, 页码 780-782出版社
NATURE PUBLISHING GROUP
DOI: 10.1038/nm0711-780
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资金
- NCI NIH HHS [R01 CA142642] Funding Source: Medline
A recent study challenges the view that radiation-induced apoptosis is beneficial in tumor therapy by showing that caspase 3-mediated apoptosis in response to ionizing radiation activates a growth signaling cascade in tumor cells, thereby stimulating tumor repopulation (pages 860-866). These results may have important implications for the clinical use of radiotherapy or chemotherapy to induce apoptosis in tumors.
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